Cutaneous inflammation differentially regulates the expression and function of Angiotensin‐II types 1 and 2 receptors in rat primary sensory neurons

Neuropathic and inflammatory pain results from cellular and molecular changes in dorsal root ganglion (DRG) neurons. The type‐2 receptor for Angiotensin‐II (AT2R) has been involved in this type of pain. However, the underlying mechanisms are poorly understood, including the role of the type‐1 recept...

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Veröffentlicht in:	Journal of neurochemistry 2020-03, Vol.152 (6), p.675-696
Hauptverfasser:	Benitez, Sergio G., Seltzer, Alicia M., Messina, Diego N., Foscolo, Mabel R., Patterson, Sean I., Acosta, Cristian G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin AT1 receptors Angiotensin AT2 receptors AT1 receptor AT2 receptor Axonogenesis Dorsal root ganglia Immunocytochemistry Immunohistochemistry Inflammation inflammatory pain mRNA Nerve endings Neuralgia neuritogenesis Neurons nociceptors Pain Receptor mechanisms Receptors Sensory neurons Subpopulations TrkA protein TrkA receptors
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