A solid-phase method for synthesis of dimeric and trimeric ligands: Identification of potent bivalent ligands of 14-3-3σ

[Display omitted] Multivalent protein-protein interactions including bivalent and trivalent interactions play a critical role in mediating a wide range of biological processes. Hence, there is a significant interest in developing molecules that can modulate those signaling pathways mediated by multi...

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Veröffentlicht in:	Bioorganic chemistry 2019-10, Vol.91, p.103141-103141, Article 103141
Hauptverfasser:	Lee, Yeongju, Chung, Brian, Ko, Daseul, Lim, Hyun-Suk
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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