Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

Binding of proteins with SH2 domains to tyrosine-phosphorylated signaling proteins is a key mechanism for transmission of biological signals within the cell. Characterization of dysregulated proteins in cell signaling pathways is important for the development of therapeutic approaches. The AKT pathw...

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Veröffentlicht in:	Cellular signalling 2019-11, Vol.63, p.109380-109380, Article 109380
Hauptverfasser:	Ehm, Patrick A.H., Lange, Fabiola, Hentschel, Carolin, Jepsen, Anneke, Glück, Madeleine, Nelson, Nina, Bettin, Bettina, de Bruyn Kops, Christina, Kirchmair, Johannes, Nalaskowski, Marcus, Jücker, Manfred
Format:	Artikel
Sprache:	eng
Schlagworte:	FLVR motif Instability SH2 domain SHIP1
Online-Zugang:	Volltext
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