Interaction of mycobacteria with Plasmin(ogen) affects phagocytosis and granuloma development

Plasminogen and plasmin are fundamental components of the fibrinolytic system that interact with microorganisms generating different immunopathological effects. The molecules of Mycobacterium tuberculosis interplaying with plasminogen have already been identified and characterized. In this work, we...

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Veröffentlicht in:	Tuberculosis (Edinburgh, Scotland) Scotland), 2019-07, Vol.117, p.36-44
Hauptverfasser:	Echeverría-Valencia, Gabriela, Silva-Miranda, Mayra, Ekaza, Euloge, Vallecillo, Antonio J., Parada, Cristina, Sada-Ovalle, Isabel, Altare, Frédéric, Espitia, Clara
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus Calmette-Guerin vaccine Bacteria BCG Cells, Cultured Cytokines - biosynthesis Fibrin Fibrinolysin - metabolism Fibrinolytic system Granuloma Granuloma - immunology Granuloma - microbiology Humans Interleukin 6 Macrophages Macrophages - microbiology Microorganisms Mycobacterium Mycobacterium bovis - isolation & purification Mycobacterium bovis - metabolism Phagocytosis Phagocytosis - physiology Plasmin Plasminogen Plasminogen - metabolism Proenzymes t-Plasminogen activator Tuberculin Tuberculosis Tuberculosis - immunology Tuberculosis - metabolism Tuberculosis - microbiology
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