Traditional Uses, Chemical Constituents and Biological Activities of Plants from the Genus Thymus
The genus Thymus (Lamiaceae) comprises about 214 species throughout the world, mainly found in North Africa, Europe, and temperate Asia zone. They are traditionally used as food additives and folk medicines. This review comprehensively summarizes information about traditional uses, chemical constitu...
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| Veröffentlicht in: | Chemistry & biodiversity 2019-09, Vol.16 (9), p.e1900254-n/a |
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| creator | Li, Xiao He, Ting Wang, Xiuhuan Shen, Meng Yan, Xin Fan, Shusheng Wang, Le Wang, Xiaoping Xu, Xiao Sui, Hong She, Gaimei |
| description | The genus Thymus (Lamiaceae) comprises about 214 species throughout the world, mainly found in North Africa, Europe, and temperate Asia zone. They are traditionally used as food additives and folk medicines. This review comprehensively summarizes information about traditional uses, chemical constituents, and biological activities of this genus and provides recommendations for future investigations. All information was gathered from scientific databases including Google Scholar, Sci‐Finder, Web of Science, ScienceDirect, and CNKI. Volatile oils are the most concerned constituents of this genus. Flavonoids, phenylpropanoids, tannins, organic acids, terpenoids, and phytosterols were also summarized. This genus plants possessed a variety of activities including antimicrobial, antioxidant, anti‐inflammatory, cytotoxic, analgesic, and antidiabetic. In brief, this review will be helpful to provide valuable data for explorations and create more interests towards Thymus genus in the future. |
| doi_str_mv | 10.1002/cbdv.201900254 |
| format | Article |
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They are traditionally used as food additives and folk medicines. This review comprehensively summarizes information about traditional uses, chemical constituents, and biological activities of this genus and provides recommendations for future investigations. All information was gathered from scientific databases including Google Scholar, Sci‐Finder, Web of Science, ScienceDirect, and CNKI. Volatile oils are the most concerned constituents of this genus. Flavonoids, phenylpropanoids, tannins, organic acids, terpenoids, and phytosterols were also summarized. This genus plants possessed a variety of activities including antimicrobial, antioxidant, anti‐inflammatory, cytotoxic, analgesic, and antidiabetic. In brief, this review will be helpful to provide valuable data for explorations and create more interests towards Thymus genus in the future.</description><identifier>ISSN: 1612-1872</identifier><identifier>EISSN: 1612-1880</identifier><identifier>DOI: 10.1002/cbdv.201900254</identifier><identifier>PMID: 31381251</identifier><language>eng</language><publisher>Switzerland: Wiley Subscription Services, Inc</publisher><subject>Analgesics ; Animals ; Anti-Infective Agents - chemistry ; Anti-Infective Agents - isolation & purification ; Anti-Infective Agents - pharmacology ; Anti-Inflammatory Agents - chemistry ; Anti-Inflammatory Agents - isolation & purification ; Anti-Inflammatory Agents - pharmacology ; Antineoplastic Agents, Phytogenic - chemistry ; Antineoplastic Agents, Phytogenic - isolation & purification ; Antineoplastic Agents, Phytogenic - pharmacology ; Antioxidants ; Antioxidants - chemistry ; Antioxidants - isolation & purification ; Antioxidants - pharmacology ; biological activity ; Constituents ; Cytotoxicity ; Diabetes mellitus ; Essential oils ; Flavonoids ; Food additives ; Humans ; Hypoglycemic Agents - chemistry ; Hypoglycemic Agents - isolation & purification ; Hypoglycemic Agents - pharmacology ; Inflammation ; Lamiaceae - chemistry ; nonvolatile compounds ; Organic acids ; Organic chemistry ; Phenylpropanoids ; Phytosterols ; Plants (botany) ; Tannins ; Terpenes ; Thymus ; traditional uses</subject><ispartof>Chemistry & biodiversity, 2019-09, Vol.16 (9), p.e1900254-n/a</ispartof><rights>2019 Wiley‐VHCA AG, Zurich, Switzerland</rights><rights>2019 Wiley-VHCA AG, Zurich, Switzerland.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3734-c3f89e5c5464f50bd71530b3dceda97d395af3cd9060aa8198ad842800a5f9293</citedby><cites>FETCH-LOGICAL-c3734-c3f89e5c5464f50bd71530b3dceda97d395af3cd9060aa8198ad842800a5f9293</cites><orcidid>0000-0003-1754-2140</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fcbdv.201900254$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fcbdv.201900254$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31381251$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Xiao</creatorcontrib><creatorcontrib>He, Ting</creatorcontrib><creatorcontrib>Wang, Xiuhuan</creatorcontrib><creatorcontrib>Shen, Meng</creatorcontrib><creatorcontrib>Yan, Xin</creatorcontrib><creatorcontrib>Fan, Shusheng</creatorcontrib><creatorcontrib>Wang, Le</creatorcontrib><creatorcontrib>Wang, Xiaoping</creatorcontrib><creatorcontrib>Xu, Xiao</creatorcontrib><creatorcontrib>Sui, Hong</creatorcontrib><creatorcontrib>She, Gaimei</creatorcontrib><title>Traditional Uses, Chemical Constituents and Biological Activities of Plants from the Genus Thymus</title><title>Chemistry & biodiversity</title><addtitle>Chem Biodivers</addtitle><description>The genus Thymus (Lamiaceae) comprises about 214 species throughout the world, mainly found in North Africa, Europe, and temperate Asia zone. They are traditionally used as food additives and folk medicines. This review comprehensively summarizes information about traditional uses, chemical constituents, and biological activities of this genus and provides recommendations for future investigations. All information was gathered from scientific databases including Google Scholar, Sci‐Finder, Web of Science, ScienceDirect, and CNKI. Volatile oils are the most concerned constituents of this genus. Flavonoids, phenylpropanoids, tannins, organic acids, terpenoids, and phytosterols were also summarized. This genus plants possessed a variety of activities including antimicrobial, antioxidant, anti‐inflammatory, cytotoxic, analgesic, and antidiabetic. In brief, this review will be helpful to provide valuable data for explorations and create more interests towards Thymus genus in the future.</description><subject>Analgesics</subject><subject>Animals</subject><subject>Anti-Infective Agents - chemistry</subject><subject>Anti-Infective Agents - isolation & purification</subject><subject>Anti-Infective Agents - pharmacology</subject><subject>Anti-Inflammatory Agents - chemistry</subject><subject>Anti-Inflammatory Agents - isolation & purification</subject><subject>Anti-Inflammatory Agents - pharmacology</subject><subject>Antineoplastic Agents, Phytogenic - chemistry</subject><subject>Antineoplastic Agents, Phytogenic - isolation & purification</subject><subject>Antineoplastic Agents, Phytogenic - pharmacology</subject><subject>Antioxidants</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - isolation & purification</subject><subject>Antioxidants - pharmacology</subject><subject>biological activity</subject><subject>Constituents</subject><subject>Cytotoxicity</subject><subject>Diabetes mellitus</subject><subject>Essential oils</subject><subject>Flavonoids</subject><subject>Food additives</subject><subject>Humans</subject><subject>Hypoglycemic Agents - chemistry</subject><subject>Hypoglycemic Agents - isolation & purification</subject><subject>Hypoglycemic Agents - pharmacology</subject><subject>Inflammation</subject><subject>Lamiaceae - chemistry</subject><subject>nonvolatile compounds</subject><subject>Organic acids</subject><subject>Organic chemistry</subject><subject>Phenylpropanoids</subject><subject>Phytosterols</subject><subject>Plants (botany)</subject><subject>Tannins</subject><subject>Terpenes</subject><subject>Thymus</subject><subject>traditional uses</subject><issn>1612-1872</issn><issn>1612-1880</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM9PwjAUxxujEUSvHk0TLx4E-2Pd2iNMRRMSPYDXpbSdlGwrrhuG_94iiIkXL319r5_3TfMB4BKjAUaI3Km5Xg8IwiI0LDoCXRxj0seco-PDPSEdcOb9MiBhzk9Bh2LKMWG4C-S0lto21lWygDNv_C1MF6a0KrSpq3xjm9ZUjYey0nBkXeHev9-GqrHrsGc8dDl8LeSWyWtXwmZh4NhUrYfTxaZs_Tk4yWXhzcW-9sDs8WGaPvUnL-PndDjpK5rQKJw5F4YpFsVRztBcJ5hRNKdaGS1FoqlgMqdKCxQjKTkWXGoeEY6QZLkggvbAzS53VbuP1vgmK61XpghfM671GSExZwllGAX0-g-6dG0dDGwpQTmKGSKBGuwoVTvva5Nnq9qWst5kGGVb-dlWfnaQHxau9rHtvDT6gP_YDoDYAZ-2MJt_4rJ0dP_2G_4FSwyQCw</recordid><startdate>201909</startdate><enddate>201909</enddate><creator>Li, Xiao</creator><creator>He, Ting</creator><creator>Wang, Xiuhuan</creator><creator>Shen, Meng</creator><creator>Yan, Xin</creator><creator>Fan, Shusheng</creator><creator>Wang, Le</creator><creator>Wang, Xiaoping</creator><creator>Xu, Xiao</creator><creator>Sui, Hong</creator><creator>She, Gaimei</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1754-2140</orcidid></search><sort><creationdate>201909</creationdate><title>Traditional Uses, Chemical Constituents and Biological Activities of Plants from the Genus Thymus</title><author>Li, Xiao ; He, Ting ; Wang, Xiuhuan ; Shen, Meng ; Yan, Xin ; Fan, Shusheng ; Wang, Le ; Wang, Xiaoping ; Xu, Xiao ; Sui, Hong ; She, Gaimei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3734-c3f89e5c5464f50bd71530b3dceda97d395af3cd9060aa8198ad842800a5f9293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Analgesics</topic><topic>Animals</topic><topic>Anti-Infective Agents - chemistry</topic><topic>Anti-Infective Agents - isolation & purification</topic><topic>Anti-Infective Agents - pharmacology</topic><topic>Anti-Inflammatory Agents - chemistry</topic><topic>Anti-Inflammatory Agents - isolation & purification</topic><topic>Anti-Inflammatory Agents - pharmacology</topic><topic>Antineoplastic Agents, Phytogenic - chemistry</topic><topic>Antineoplastic Agents, Phytogenic - isolation & purification</topic><topic>Antineoplastic Agents, Phytogenic - pharmacology</topic><topic>Antioxidants</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - isolation & purification</topic><topic>Antioxidants - pharmacology</topic><topic>biological activity</topic><topic>Constituents</topic><topic>Cytotoxicity</topic><topic>Diabetes mellitus</topic><topic>Essential oils</topic><topic>Flavonoids</topic><topic>Food additives</topic><topic>Humans</topic><topic>Hypoglycemic Agents - chemistry</topic><topic>Hypoglycemic Agents - isolation & purification</topic><topic>Hypoglycemic Agents - pharmacology</topic><topic>Inflammation</topic><topic>Lamiaceae - chemistry</topic><topic>nonvolatile compounds</topic><topic>Organic acids</topic><topic>Organic chemistry</topic><topic>Phenylpropanoids</topic><topic>Phytosterols</topic><topic>Plants (botany)</topic><topic>Tannins</topic><topic>Terpenes</topic><topic>Thymus</topic><topic>traditional uses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Xiao</creatorcontrib><creatorcontrib>He, Ting</creatorcontrib><creatorcontrib>Wang, Xiuhuan</creatorcontrib><creatorcontrib>Shen, Meng</creatorcontrib><creatorcontrib>Yan, Xin</creatorcontrib><creatorcontrib>Fan, Shusheng</creatorcontrib><creatorcontrib>Wang, Le</creatorcontrib><creatorcontrib>Wang, Xiaoping</creatorcontrib><creatorcontrib>Xu, Xiao</creatorcontrib><creatorcontrib>Sui, Hong</creatorcontrib><creatorcontrib>She, Gaimei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chemistry & biodiversity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Xiao</au><au>He, Ting</au><au>Wang, Xiuhuan</au><au>Shen, Meng</au><au>Yan, Xin</au><au>Fan, Shusheng</au><au>Wang, Le</au><au>Wang, Xiaoping</au><au>Xu, Xiao</au><au>Sui, Hong</au><au>She, Gaimei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Traditional Uses, Chemical Constituents and Biological Activities of Plants from the Genus Thymus</atitle><jtitle>Chemistry & biodiversity</jtitle><addtitle>Chem Biodivers</addtitle><date>2019-09</date><risdate>2019</risdate><volume>16</volume><issue>9</issue><spage>e1900254</spage><epage>n/a</epage><pages>e1900254-n/a</pages><issn>1612-1872</issn><eissn>1612-1880</eissn><abstract>The genus Thymus (Lamiaceae) comprises about 214 species throughout the world, mainly found in North Africa, Europe, and temperate Asia zone. They are traditionally used as food additives and folk medicines. This review comprehensively summarizes information about traditional uses, chemical constituents, and biological activities of this genus and provides recommendations for future investigations. All information was gathered from scientific databases including Google Scholar, Sci‐Finder, Web of Science, ScienceDirect, and CNKI. Volatile oils are the most concerned constituents of this genus. Flavonoids, phenylpropanoids, tannins, organic acids, terpenoids, and phytosterols were also summarized. This genus plants possessed a variety of activities including antimicrobial, antioxidant, anti‐inflammatory, cytotoxic, analgesic, and antidiabetic. In brief, this review will be helpful to provide valuable data for explorations and create more interests towards Thymus genus in the future.</abstract><cop>Switzerland</cop><pub>Wiley Subscription Services, Inc</pub><pmid>31381251</pmid><doi>10.1002/cbdv.201900254</doi><tpages>33</tpages><orcidid>https://orcid.org/0000-0003-1754-2140</orcidid></addata></record> |
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| subjects | Analgesics Animals Anti-Infective Agents - chemistry Anti-Infective Agents - isolation & purification Anti-Infective Agents - pharmacology Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - isolation & purification Anti-Inflammatory Agents - pharmacology Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Antioxidants Antioxidants - chemistry Antioxidants - isolation & purification Antioxidants - pharmacology biological activity Constituents Cytotoxicity Diabetes mellitus Essential oils Flavonoids Food additives Humans Hypoglycemic Agents - chemistry Hypoglycemic Agents - isolation & purification Hypoglycemic Agents - pharmacology Inflammation Lamiaceae - chemistry nonvolatile compounds Organic acids Organic chemistry Phenylpropanoids Phytosterols Plants (botany) Tannins Terpenes Thymus traditional uses |
| title | Traditional Uses, Chemical Constituents and Biological Activities of Plants from the Genus Thymus |
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