Effect of Topical Corticosteroids on Early Postoperative Intraocular Pressure Following Combined Cataract and Trabecular Microbypass Surgery

To evaluate the early postoperative outcomes of trabecular micro-bypass stents and concomitant cataract surgery (TMS-CS) with and without postoperative corticosteroid therapy. Prospective, interventional matched, consecutive case series comparing outcomes of open-angle glaucoma patients who underwen...

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Veröffentlicht in:Journal of ocular pharmacology and therapeutics 2019-09, Vol.35 (7), p.413-420
Hauptverfasser: Salimi, Ali, Winter, Aaron, Li, Cody, Harasymowycz, Paul, Saheb, Hady
Format: Artikel
Sprache:eng
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Zusammenfassung:To evaluate the early postoperative outcomes of trabecular micro-bypass stents and concomitant cataract surgery (TMS-CS) with and without postoperative corticosteroid therapy. Prospective, interventional matched, consecutive case series comparing outcomes of open-angle glaucoma patients who underwent TMS-CS with and without postoperative corticosteroid therapy. Primary outcome was intraocular pressure (IOP) changes up to 6 months postoperatively and the secondary outcomes included number of postoperative medications, IOP spikes, peripheral anterior synechia (PAS), and best-corrected visual acuity improvements. The clinical outcomes of 97 eyes-49 in the steroid group age- and IOP-matched with 48 in the nonsteroid group-were analyzed. Baseline IOP in steroid and nonsteroid groups were 16.22 ± 3.98 and 16.04 ± 3.99 (  = 0.822), respectively. Both IOP and number of antiglaucoma medications significantly decreased postoperatively (  
ISSN:1080-7683
1557-7732
DOI:10.1089/jop.2019.0019