Envelope-deforming antiviral peptide derived from influenza virus M2 protein

Molecules interfering with lipid bilayer function exhibit strong antiviral activity against a broad range of enveloped viruses, with a lower risk of resistance development than that for viral protein-targeting drugs. Amphipathic peptides are rich sources of such membrane-interacting antivirals. Here...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2019-09, Vol.517 (3), p.507-512
Hauptverfasser:	Jung, Younghun, Kong, Byoungjae, Moon, Seokoh, Yu, Seok-Hyeon, Chung, Jinhyo, Ban, Choongjin, Chung, Woo-Jae, Kim, Sung-Gun, Kweon, Dae-Hyuk
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amphipathic peptide Animals Antiviral Agents - chemical synthesis Antiviral Agents - pharmacology Antiviral peptide Cell Membrane - chemistry Cell Membrane - drug effects Cell Membrane - virology Dogs Hydrophobic and Hydrophilic Interactions Hydrophobic moment Influenza A Virus, H1N1 Subtype - drug effects Influenza A Virus, H1N1 Subtype - growth & development Influenza A Virus, H1N1 Subtype - ultrastructure Influenza virus Inhibitory Concentration 50 Lipid Bilayers - chemistry Liposomes - chemistry M2 protein Madin Darby Canine Kidney Cells Membrane deformation Peptides - chemical synthesis Peptides - pharmacology Structure-Activity Relationship Viral Load - drug effects Viral Matrix Proteins - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!