How Basic Can You Be?

[...]had arterial blood gas measurements been performed, the pH would have been approximately 8.00 and thus the highest nonlethal recorded pH in the medical literature. [...]hypovolemia increased renal H+ secretion and HCO3− reabsorption via activation of the renin-angiotensin-aldosterone pathway. [...

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Veröffentlicht in:Annals of the American Thoracic Society 2019-08, Vol.16 (8), p.1057-1061
Hauptverfasser: Nadler, Samuel T, Suri, Joshun, Swenson, Erik R
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container_title Annals of the American Thoracic Society
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creator Nadler, Samuel T
Suri, Joshun
Swenson, Erik R
description [...]had arterial blood gas measurements been performed, the pH would have been approximately 8.00 and thus the highest nonlethal recorded pH in the medical literature. [...]hypovolemia increased renal H+ secretion and HCO3− reabsorption via activation of the renin-angiotensin-aldosterone pathway. [...]hypochloremia decreased bicarbonate secretion in the distal nephron by reducing the activity of the bicarbonate–chloride exchange transporter. Metabolic Acidosis Our patient’s third acid–base disturbance was a lactic acidosis. Because the serum chloride concentration was below the detectable limit (
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Because the serum chloride concentration was below the detectable limit (&lt;65 mM), calculations to evaluate for concomitant anion and nonanion gap acidoses could not be performed.</description><identifier>ISSN: 2329-6933</identifier><identifier>EISSN: 2325-6621</identifier><identifier>DOI: 10.1513/AnnalsATS.201810-670CC</identifier><identifier>PMID: 31368806</identifier><language>eng</language><publisher>United States: American Thoracic Society</publisher><subject>Acids ; Blood ; Carbon dioxide ; Case reports ; Critical care ; Family medical history ; Hemoglobin ; Homeostasis ; Intensive care ; Intubation ; Laboratories ; Medicine ; Metabolism ; Patients ; Potassium ; Systematic review ; Tomography ; Ventilators ; Vomiting</subject><ispartof>Annals of the American Thoracic Society, 2019-08, Vol.16 (8), p.1057-1061</ispartof><rights>Copyright American Thoracic Society Aug 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-caea4b60a1c16d0234f37036d481dea52cef8ece6daf105776eece3eaa7ba0953</citedby><cites>FETCH-LOGICAL-c339t-caea4b60a1c16d0234f37036d481dea52cef8ece6daf105776eece3eaa7ba0953</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31368806$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nadler, Samuel T</creatorcontrib><creatorcontrib>Suri, Joshun</creatorcontrib><creatorcontrib>Swenson, Erik R</creatorcontrib><title>How Basic Can You Be?</title><title>Annals of the American Thoracic Society</title><addtitle>Ann Am Thorac Soc</addtitle><description>[...]had arterial blood gas measurements been performed, the pH would have been approximately 8.00 and thus the highest nonlethal recorded pH in the medical literature. 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source American Thoracic Society (ATS) Journals Online; Alma/SFX Local Collection
subjects Acids
Blood
Carbon dioxide
Case reports
Critical care
Family medical history
Hemoglobin
Homeostasis
Intensive care
Intubation
Laboratories
Medicine
Metabolism
Patients
Potassium
Systematic review
Tomography
Ventilators
Vomiting
title How Basic Can You Be?
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