How Basic Can You Be?
[...]had arterial blood gas measurements been performed, the pH would have been approximately 8.00 and thus the highest nonlethal recorded pH in the medical literature. [...]hypovolemia increased renal H+ secretion and HCO3− reabsorption via activation of the renin-angiotensin-aldosterone pathway. [...
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Veröffentlicht in: | Annals of the American Thoracic Society 2019-08, Vol.16 (8), p.1057-1061 |
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creator | Nadler, Samuel T Suri, Joshun Swenson, Erik R |
description | [...]had arterial blood gas measurements been performed, the pH would have been approximately 8.00 and thus the highest nonlethal recorded pH in the medical literature. [...]hypovolemia increased renal H+ secretion and HCO3− reabsorption via activation of the renin-angiotensin-aldosterone pathway. [...]hypochloremia decreased bicarbonate secretion in the distal nephron by reducing the activity of the bicarbonate–chloride exchange transporter. Metabolic Acidosis Our patient’s third acid–base disturbance was a lactic acidosis. Because the serum chloride concentration was below the detectable limit ( |
doi_str_mv | 10.1513/AnnalsATS.201810-670CC |
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[...]hypovolemia increased renal H+ secretion and HCO3− reabsorption via activation of the renin-angiotensin-aldosterone pathway. [...]hypochloremia decreased bicarbonate secretion in the distal nephron by reducing the activity of the bicarbonate–chloride exchange transporter. Metabolic Acidosis Our patient’s third acid–base disturbance was a lactic acidosis. Because the serum chloride concentration was below the detectable limit (<65 mM), calculations to evaluate for concomitant anion and nonanion gap acidoses could not be performed.</description><identifier>ISSN: 2329-6933</identifier><identifier>EISSN: 2325-6621</identifier><identifier>DOI: 10.1513/AnnalsATS.201810-670CC</identifier><identifier>PMID: 31368806</identifier><language>eng</language><publisher>United States: American Thoracic Society</publisher><subject>Acids ; Blood ; Carbon dioxide ; Case reports ; Critical care ; Family medical history ; Hemoglobin ; Homeostasis ; Intensive care ; Intubation ; Laboratories ; Medicine ; Metabolism ; Patients ; Potassium ; Systematic review ; Tomography ; Ventilators ; Vomiting</subject><ispartof>Annals of the American Thoracic Society, 2019-08, Vol.16 (8), p.1057-1061</ispartof><rights>Copyright American Thoracic Society Aug 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-caea4b60a1c16d0234f37036d481dea52cef8ece6daf105776eece3eaa7ba0953</citedby><cites>FETCH-LOGICAL-c339t-caea4b60a1c16d0234f37036d481dea52cef8ece6daf105776eece3eaa7ba0953</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31368806$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nadler, Samuel T</creatorcontrib><creatorcontrib>Suri, Joshun</creatorcontrib><creatorcontrib>Swenson, Erik R</creatorcontrib><title>How Basic Can You Be?</title><title>Annals of the American Thoracic Society</title><addtitle>Ann Am Thorac Soc</addtitle><description>[...]had arterial blood gas measurements been performed, the pH would have been approximately 8.00 and thus the highest nonlethal recorded pH in the medical literature. [...]hypovolemia increased renal H+ secretion and HCO3− reabsorption via activation of the renin-angiotensin-aldosterone pathway. [...]hypochloremia decreased bicarbonate secretion in the distal nephron by reducing the activity of the bicarbonate–chloride exchange transporter. Metabolic Acidosis Our patient’s third acid–base disturbance was a lactic acidosis. Because the serum chloride concentration was below the detectable limit (<65 mM), calculations to evaluate for concomitant anion and nonanion gap acidoses could not be performed.</description><subject>Acids</subject><subject>Blood</subject><subject>Carbon dioxide</subject><subject>Case reports</subject><subject>Critical care</subject><subject>Family medical history</subject><subject>Hemoglobin</subject><subject>Homeostasis</subject><subject>Intensive care</subject><subject>Intubation</subject><subject>Laboratories</subject><subject>Medicine</subject><subject>Metabolism</subject><subject>Patients</subject><subject>Potassium</subject><subject>Systematic review</subject><subject>Tomography</subject><subject>Ventilators</subject><subject>Vomiting</subject><issn>2329-6933</issn><issn>2325-6621</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkE1Lw0AQhhdRbKk9ei0BL15Sd3eyXydpg1qh4MF68LRsNxNoaZOabRD_vdum9uBcZgaedwYeQkaMjplg8DCpKrcJk8X7mFOmGU2lonl-QfocuEil5OzyOJtUGoAeGYawprG0YFqZa9IDBlJrKvvkdlZ_J1MXVj7JXZV81m0yxccbclXGDzg89QH5eH5a5LN0_vbymk_mqQcw-9Q7dNlSUsc8kwXlkJWgKMgi06xAJ7jHUqNHWbiSUaGUxLgBOqeWjhoBA3Lf3d019VeLYW-3q-Bxs3EV1m2wnEulBMsUj-jdP3Rdt83BQ6S0kYprYSIlO8o3dQgNlnbXrLau-bGM2oM7e3ZnO3f26C4GR6fz7XKLxTn2Zwp-Ab0naPQ</recordid><startdate>201908</startdate><enddate>201908</enddate><creator>Nadler, Samuel T</creator><creator>Suri, Joshun</creator><creator>Swenson, Erik R</creator><general>American Thoracic Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>201908</creationdate><title>How Basic Can You Be?</title><author>Nadler, Samuel T ; 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source | American Thoracic Society (ATS) Journals Online; Alma/SFX Local Collection |
subjects | Acids Blood Carbon dioxide Case reports Critical care Family medical history Hemoglobin Homeostasis Intensive care Intubation Laboratories Medicine Metabolism Patients Potassium Systematic review Tomography Ventilators Vomiting |
title | How Basic Can You Be? |
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