Preparation of Lipid Nanodisks Containing Apolipoprotein E-Derived Synthetic Peptides for Biocompatible Delivery Vehicles Targeting Low-Density Lipoprotein Receptor

High-density lipoprotein (HDL) particles that are formed in vivo adopt a disk-shaped structure, in which the periphery of the discoidal phospholipid bilayer is surrounded by apolipoprotein. Such discoidal nanoparticles can be reconstituted with certain apolipoproteins and phospholipids and are commo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biological & pharmaceutical bulletin 2019/08/01, Vol.42(8), pp.1376-1383
Hauptverfasser:	Tanaka, Masafumi, Hasegawa, Mariko, Yoshimoto, Natsumi, Hoshikawa, Kozue, Mukai, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Animals Apolipoprotein E Apolipoproteins Apolipoproteins E Biocompatibility Blood circulation delivery vehicle Density Dimyristoylphosphatidylcholine - administration & dosage Dimyristoylphosphatidylcholine - pharmacokinetics Drug Carriers - administration & dosage Drug Carriers - pharmacokinetics Hep G2 Cells High density lipoprotein Humans lipid nanodisk Lipids Lipoproteins Low density lipoprotein low-density lipoprotein receptor Male Mice, Inbred BALB C Mice, Nude Nanoparticles Nanostructures - administration & dosage Peptides Peptides - administration & dosage Peptides - pharmacokinetics Phospholipids Receptor density Receptors, LDL - metabolism Spleen Synthetic peptides Tissue Distribution Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!