Effects of Histone Deacetylase Inhibitors on the Development of Epilepsy and Psychiatric Comorbidity in WAG/Rij Rats

Epigenetic mechanisms, such as alterations in histone acetylation based on histone deacetylases (HDACs) activity, have been linked not only to normal brain function but also to several brain disorders including epilepsy and the epileptogenic process. In WAG/Rij rats, a genetic model of absence epile...

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Veröffentlicht in:	Molecular neurobiology 2020, Vol.57 (1), p.408-421
Hauptverfasser:	Citraro, Rita, Leo, Antonio, De Caro, Carmen, Nesci, Valentina, Gallo Cantafio, Maria E., Amodio, Nicola, Mattace Raso, Giuseppina, Lama, Adriano, Russo, Roberto, Calignano, Antonio, Tallarico, Martina, Russo, Emilio, De Sarro, Giovambattista
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Biomedical and Life Sciences Biomedicine Brain Cell Biology Cognitive ability Comorbidity Convulsions & seizures EEG Epilepsy Histone deacetylase Histone H3 Inhibitors Neurobiology Neurology Neurosciences Seizures Sodium Sodium butyrate Valproic acid Western blotting Withdrawal
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