UPLC–QTOF/MS‐based metabolomics reveals the mechanism of chronic unpredictable mild stress‐induced hypertension in rats

Hypertension is a common chronic disease, and it is the strongest risk factor for cardiovascular disease. Recently, the number of patients with hypertension‐related complications has increased significantly, adding a heavy burden to the public health system. It is known that chronic stress plays an...

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Veröffentlicht in:	Biomedical chromatography 2019-10, Vol.33 (10), p.e4619-n/a
Hauptverfasser:	Wu, Qiong, Xia, De‐Meng, Lan, Fen, Wang, Yang‐Kai, Tan, Xing, Sun, Jia‐Cen, Wang, Wei‐Zhong, Wang, Rui, Peng, Xiao‐Dong, Liu, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - blood Amino Acids - metabolism Animals Blood Pressure - physiology Chromatography, High Pressure Liquid - methods Chronic Disease chronic stress Corticosterone - blood Corticosterone - metabolism Disease Models, Animal hypertension Hypertension - metabolism Mass Spectrometry - methods Metabolome - physiology metabolomics Metabolomics - methods Norepinephrine - blood Norepinephrine - metabolism Phospholipids - blood Phospholipids - metabolism Rats Rats, Sprague-Dawley Stress, Psychological - metabolism UPLC
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