Effect and mechanism of verbascoside on hypoxic memory injury in plateau

Verbascoside is a water‐soluble natural phenylethanoid glycoside and distributes widely in plants. It has been proved with antioxidant, neuroprotective, anti‐inflammatory, antibacterial, and immunomodulatory bioactivities. In this experiment, the effect and mechanism of verbascoside on hypoxic memor...

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Veröffentlicht in:	Phytotherapy research 2019-10, Vol.33 (10), p.2692-2701
Hauptverfasser:	Li, Maoxing, Zhu, Yuting, Li, Jing, Chen, Liping, Tao, Wendi, Li, Xiaoling, Qiu, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Altitude Animals Antioxidants Apoptosis Brain Caspase eight‐arm maze Enzymatic activity Enzyme activity Gene expression Glucosides - pharmacology Glucosides - therapeutic use High altitude Hippocampus Hippocampus - drug effects Hypoxia hypoxia memory impairment Immunomodulation Inflammation Male Memory Disorders - drug therapy Memory Disorders - etiology mTOR signaling pathway Neuroprotection Oxidative stress Phenols - pharmacology Phenols - therapeutic use Rats Rats, Wistar Short term memory Signal transduction TOR protein TOR Serine-Threonine Kinases - metabolism verbascoside
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