Clinical characteristics and outcome of dogs with presumed primary renal lymphoma
Objectives To characterise the presentation, clinicopathologic data and outcome of 29 dogs with presumed primary renal lymphoma. Materials and Methods Retrospective analysis of medical records of dogs with suspected primary renal lymphoma from 11 institutions. Results All dogs were substage b, and l...
Gespeichert in:
Veröffentlicht in: | Journal of small animal practice 2019-11, Vol.60 (11), p.663-670 |
---|---|
Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 670 |
---|---|
container_issue | 11 |
container_start_page | 663 |
container_title | Journal of small animal practice |
container_volume | 60 |
creator | Taylor, A. Finotello, R. Vilar‐Saavedra, P. Couto, C. G. Benigni, L. Lara‐Garcia, A. |
description | Objectives
To characterise the presentation, clinicopathologic data and outcome of 29 dogs with presumed primary renal lymphoma.
Materials and Methods
Retrospective analysis of medical records of dogs with suspected primary renal lymphoma from 11 institutions.
Results
All dogs were substage b, and lethargy and gastrointestinal signs were common presenting complaints, as were azotaemia (n=25; 86%) and erythrocytosis (n=15; 51%) on biochemical testing. Ultrasonography typically revealed bilateral renal lesions (n=23; 79%), renomegaly (n=22; 76%) and abdominal lymphadenopathy (n=14; 48%). Chemotherapy was the only treatment in 23 dogs, of which 11 responded, all considered partial responses. For all dogs the median progression‐free survival and median overall survival times were 10 days (range: 1 to 126) and 12 days (range: 1 to 212), respectively, and for dogs that responded to chemotherapy 41 days (range: 10 to 126) and 47 days (range: 10 to 212), respectively.
Clinical Significance
Primary renal lymphoma in dogs appears to be associated with a poor prognosis and short‐lived response to chemotherapy. |
doi_str_mv | 10.1111/jsap.13059 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2267404673</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2267404673</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3579-6b25058048b73ab9a25e5e963e5b4d9983d9ec18aab1c88fc0982874cefd9e863</originalsourceid><addsrcrecordid>eNp9kF1LwzAUhoMobk5v_AES8EaEznw2yeUYfiKoqNclTVPX0TYzaRn792Z2euGF5ybncJ68JA8ApxhNcayrZdCrKaaIqz0wxoLJhEsi9sEYIUISxjEagaMQlnFMmUCHYEQxTRmWaAxe5nXVVkbX0Cy016azvgpdZQLUbQFd3xnXWOhKWLiPANdVt4Arb0Pf2CI2VaP9Bnrbxvv1plktXKOPwUGp62BPducEvN9cv83vksen2_v57DExlAuVpDnhiEvEZC6ozpUm3HKrUmp5zgqlJC2UNVhqnWMjZWmQkkQKZmwZFzKlE3Ax5K68--xt6LKmCsbWtW6t60NGSCoYYqmgET3_gy5d7-OjIxVVMKKwIJG6HCjjXQjeltnugxlG2VZ0thWdfYuO8Nkuss-ji1_0x2wE8ACsq9pu_onKHl5nz0PoF0xaiCw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2313429172</pqid></control><display><type>article</type><title>Clinical characteristics and outcome of dogs with presumed primary renal lymphoma</title><source>Access via Wiley Online Library</source><creator>Taylor, A. ; Finotello, R. ; Vilar‐Saavedra, P. ; Couto, C. G. ; Benigni, L. ; Lara‐Garcia, A.</creator><creatorcontrib>Taylor, A. ; Finotello, R. ; Vilar‐Saavedra, P. ; Couto, C. G. ; Benigni, L. ; Lara‐Garcia, A.</creatorcontrib><description>Objectives
To characterise the presentation, clinicopathologic data and outcome of 29 dogs with presumed primary renal lymphoma.
Materials and Methods
Retrospective analysis of medical records of dogs with suspected primary renal lymphoma from 11 institutions.
Results
All dogs were substage b, and lethargy and gastrointestinal signs were common presenting complaints, as were azotaemia (n=25; 86%) and erythrocytosis (n=15; 51%) on biochemical testing. Ultrasonography typically revealed bilateral renal lesions (n=23; 79%), renomegaly (n=22; 76%) and abdominal lymphadenopathy (n=14; 48%). Chemotherapy was the only treatment in 23 dogs, of which 11 responded, all considered partial responses. For all dogs the median progression‐free survival and median overall survival times were 10 days (range: 1 to 126) and 12 days (range: 1 to 212), respectively, and for dogs that responded to chemotherapy 41 days (range: 10 to 126) and 47 days (range: 10 to 212), respectively.
Clinical Significance
Primary renal lymphoma in dogs appears to be associated with a poor prognosis and short‐lived response to chemotherapy.</description><identifier>ISSN: 0022-4510</identifier><identifier>EISSN: 1748-5827</identifier><identifier>DOI: 10.1111/jsap.13059</identifier><identifier>PMID: 31364180</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Chemotherapy ; Kidneys ; Lymphadenopathy ; Lymphoma ; Medical prognosis ; Medical records ; Polycythemia ; Survival ; Ultrasound</subject><ispartof>Journal of small animal practice, 2019-11, Vol.60 (11), p.663-670</ispartof><rights>2019 British Small Animal Veterinary Association</rights><rights>2019 British Small Animal Veterinary Association.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3579-6b25058048b73ab9a25e5e963e5b4d9983d9ec18aab1c88fc0982874cefd9e863</citedby><cites>FETCH-LOGICAL-c3579-6b25058048b73ab9a25e5e963e5b4d9983d9ec18aab1c88fc0982874cefd9e863</cites><orcidid>0000-0003-3852-0127</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjsap.13059$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjsap.13059$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31364180$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Taylor, A.</creatorcontrib><creatorcontrib>Finotello, R.</creatorcontrib><creatorcontrib>Vilar‐Saavedra, P.</creatorcontrib><creatorcontrib>Couto, C. G.</creatorcontrib><creatorcontrib>Benigni, L.</creatorcontrib><creatorcontrib>Lara‐Garcia, A.</creatorcontrib><title>Clinical characteristics and outcome of dogs with presumed primary renal lymphoma</title><title>Journal of small animal practice</title><addtitle>J Small Anim Pract</addtitle><description>Objectives
To characterise the presentation, clinicopathologic data and outcome of 29 dogs with presumed primary renal lymphoma.
Materials and Methods
Retrospective analysis of medical records of dogs with suspected primary renal lymphoma from 11 institutions.
Results
All dogs were substage b, and lethargy and gastrointestinal signs were common presenting complaints, as were azotaemia (n=25; 86%) and erythrocytosis (n=15; 51%) on biochemical testing. Ultrasonography typically revealed bilateral renal lesions (n=23; 79%), renomegaly (n=22; 76%) and abdominal lymphadenopathy (n=14; 48%). Chemotherapy was the only treatment in 23 dogs, of which 11 responded, all considered partial responses. For all dogs the median progression‐free survival and median overall survival times were 10 days (range: 1 to 126) and 12 days (range: 1 to 212), respectively, and for dogs that responded to chemotherapy 41 days (range: 10 to 126) and 47 days (range: 10 to 212), respectively.
Clinical Significance
Primary renal lymphoma in dogs appears to be associated with a poor prognosis and short‐lived response to chemotherapy.</description><subject>Chemotherapy</subject><subject>Kidneys</subject><subject>Lymphadenopathy</subject><subject>Lymphoma</subject><subject>Medical prognosis</subject><subject>Medical records</subject><subject>Polycythemia</subject><subject>Survival</subject><subject>Ultrasound</subject><issn>0022-4510</issn><issn>1748-5827</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp9kF1LwzAUhoMobk5v_AES8EaEznw2yeUYfiKoqNclTVPX0TYzaRn792Z2euGF5ybncJ68JA8ApxhNcayrZdCrKaaIqz0wxoLJhEsi9sEYIUISxjEagaMQlnFMmUCHYEQxTRmWaAxe5nXVVkbX0Cy016azvgpdZQLUbQFd3xnXWOhKWLiPANdVt4Arb0Pf2CI2VaP9Bnrbxvv1plktXKOPwUGp62BPducEvN9cv83vksen2_v57DExlAuVpDnhiEvEZC6ozpUm3HKrUmp5zgqlJC2UNVhqnWMjZWmQkkQKZmwZFzKlE3Ax5K68--xt6LKmCsbWtW6t60NGSCoYYqmgET3_gy5d7-OjIxVVMKKwIJG6HCjjXQjeltnugxlG2VZ0thWdfYuO8Nkuss-ji1_0x2wE8ACsq9pu_onKHl5nz0PoF0xaiCw</recordid><startdate>201911</startdate><enddate>201911</enddate><creator>Taylor, A.</creator><creator>Finotello, R.</creator><creator>Vilar‐Saavedra, P.</creator><creator>Couto, C. G.</creator><creator>Benigni, L.</creator><creator>Lara‐Garcia, A.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7QR</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3852-0127</orcidid></search><sort><creationdate>201911</creationdate><title>Clinical characteristics and outcome of dogs with presumed primary renal lymphoma</title><author>Taylor, A. ; Finotello, R. ; Vilar‐Saavedra, P. ; Couto, C. G. ; Benigni, L. ; Lara‐Garcia, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3579-6b25058048b73ab9a25e5e963e5b4d9983d9ec18aab1c88fc0982874cefd9e863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Chemotherapy</topic><topic>Kidneys</topic><topic>Lymphadenopathy</topic><topic>Lymphoma</topic><topic>Medical prognosis</topic><topic>Medical records</topic><topic>Polycythemia</topic><topic>Survival</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Taylor, A.</creatorcontrib><creatorcontrib>Finotello, R.</creatorcontrib><creatorcontrib>Vilar‐Saavedra, P.</creatorcontrib><creatorcontrib>Couto, C. G.</creatorcontrib><creatorcontrib>Benigni, L.</creatorcontrib><creatorcontrib>Lara‐Garcia, A.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of small animal practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Taylor, A.</au><au>Finotello, R.</au><au>Vilar‐Saavedra, P.</au><au>Couto, C. G.</au><au>Benigni, L.</au><au>Lara‐Garcia, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical characteristics and outcome of dogs with presumed primary renal lymphoma</atitle><jtitle>Journal of small animal practice</jtitle><addtitle>J Small Anim Pract</addtitle><date>2019-11</date><risdate>2019</risdate><volume>60</volume><issue>11</issue><spage>663</spage><epage>670</epage><pages>663-670</pages><issn>0022-4510</issn><eissn>1748-5827</eissn><abstract>Objectives
To characterise the presentation, clinicopathologic data and outcome of 29 dogs with presumed primary renal lymphoma.
Materials and Methods
Retrospective analysis of medical records of dogs with suspected primary renal lymphoma from 11 institutions.
Results
All dogs were substage b, and lethargy and gastrointestinal signs were common presenting complaints, as were azotaemia (n=25; 86%) and erythrocytosis (n=15; 51%) on biochemical testing. Ultrasonography typically revealed bilateral renal lesions (n=23; 79%), renomegaly (n=22; 76%) and abdominal lymphadenopathy (n=14; 48%). Chemotherapy was the only treatment in 23 dogs, of which 11 responded, all considered partial responses. For all dogs the median progression‐free survival and median overall survival times were 10 days (range: 1 to 126) and 12 days (range: 1 to 212), respectively, and for dogs that responded to chemotherapy 41 days (range: 10 to 126) and 47 days (range: 10 to 212), respectively.
Clinical Significance
Primary renal lymphoma in dogs appears to be associated with a poor prognosis and short‐lived response to chemotherapy.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>31364180</pmid><doi>10.1111/jsap.13059</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-3852-0127</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0022-4510 |
ispartof | Journal of small animal practice, 2019-11, Vol.60 (11), p.663-670 |
issn | 0022-4510 1748-5827 |
language | eng |
recordid | cdi_proquest_miscellaneous_2267404673 |
source | Access via Wiley Online Library |
subjects | Chemotherapy Kidneys Lymphadenopathy Lymphoma Medical prognosis Medical records Polycythemia Survival Ultrasound |
title | Clinical characteristics and outcome of dogs with presumed primary renal lymphoma |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T09%3A29%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20characteristics%20and%20outcome%20of%20dogs%20with%20presumed%20primary%20renal%20lymphoma&rft.jtitle=Journal%20of%20small%20animal%20practice&rft.au=Taylor,%20A.&rft.date=2019-11&rft.volume=60&rft.issue=11&rft.spage=663&rft.epage=670&rft.pages=663-670&rft.issn=0022-4510&rft.eissn=1748-5827&rft_id=info:doi/10.1111/jsap.13059&rft_dat=%3Cproquest_cross%3E2267404673%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2313429172&rft_id=info:pmid/31364180&rfr_iscdi=true |