PLD1 promotes dendritic spine morphogenesis via activating PKD1

Dendritic spines on the dendrites of pyramidal neurons are one of the most important components for excitatory synapses, where excitatory information exchanges and integrates. The defects of dendritic spine development have been closely connected with many nervous system diseases including autism, i...

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Veröffentlicht in:	Molecular and cellular neuroscience 2019-09, Vol.99, p.103394-103394, Article 103394
Hauptverfasser:	Li, Wen-Qi, Luo, Li-Da, Hu, Zhi-Wen, Lyu, Tian-Jie, Cen, Cheng, Wang, Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cells, Cultured Dendritic spine morphogenesis Dendritic Spines - metabolism Dendritic Spines - physiology Mice Neurogenesis Phospholipase D - antagonists & inhibitors Phospholipase D - metabolism Phospholipase D1 (PLD1) Protein Binding Protein kinase D1 (PKD1) Rats Rats, Sprague-Dawley TRPP Cation Channels - metabolism
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