Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry

Polyomaviruses, like the BK-polyomavirus (BKPyV), can cause severe pathologies in immunocompromised patients. However, since highly effective antivirals are currently not available, methods measuring the impact of potential antiviral agents are required. Here, a dual fluorescence reporter that allow...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of visualized experiments 2019-07 (149)
Hauptverfasser:	Korth, Johannes, Sertznig, Helene, Moyrer, Siegfried, Doevelaar, Adrian Atilla Nicolas, Westhoff, Timm Henning, Babel, Nina, Witzke, Oliver, Kribben, Andreas, Dittmer, Ulf, Widera, Marek
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - pharmacology BK Virus - drug effects BK Virus - genetics BK Virus - isolation & purification BK Virus - metabolism Flow Cytometry HEK293 Cells Humans Luminescent Proteins - genetics Luminescent Proteins - metabolism Polyomavirus Infections - blood Polyomavirus Infections - virology Regulatory Sequences, Nucleic Acid - genetics Transcription, Genetic - drug effects Tumor Virus Infections - blood Tumor Virus Infections - virology
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!