Lactobacillus plantarum PS128 ameliorates 2,5-Dimethoxy-4-iodoamphetamine-induced tic-like behaviors via its influences on the microbiota–gut-brain-axis

[Display omitted] •Serotonin receptor agonist DOI causes tic-like behaviors and gut dysbiosis in rat.•DOI triggers hyperactive signaling in mesocortical and nigrostriatal pathways.•PS128 alleviates DOI-induced behavior and hyperactive signaling.•PS128 modulates enteric serotonergic system and stabil...

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Veröffentlicht in:	Brain research bulletin 2019-11, Vol.153, p.59-73
Hauptverfasser:	Liao, Jian-Fu, Cheng, Yun-Fang, Li, Shiao-Wen, Lee, Wang-Tso, Hsu, Chih-Chieh, Wu, Chien-Chen, Jeng, One-Jang, Wang, Sabrina, Tsai, Ying-Chieh
Format:	Artikel
Sprache:	eng
Schlagworte:	Dopamine Lactobacillus plantarum PS128 Microbiome-gut-brain-axis Psychobiotic Tics Tourette syndrome
Online-Zugang:	Volltext
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