Identification of novel therapeutic targets for neuropathic pain based on gene expression patterns

Neuropathic pain (NP) caused by nerve injury or dysfunction is one of the most challenging neurological diseases. In‐depth study of disease signatures contributes to the development of novel target treatment for NP. In this study, we analyzed expression profiles of qualified NP datasets (GSE24982 an...

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Veröffentlicht in:	Journal of cellular physiology 2019-11, Vol.234 (11), p.19494-19501
Hauptverfasser:	Zhu, Di, Liu, Kang, Wan, Cheng‐Liang, Lu, Jangnin, Zhao, Hong‐Xia
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Biomarkers Biomarkers - analysis Computational Biology differentially expressed genes Female Gene expression Gene Expression Regulation - genetics Gene Ontology Gene Regulatory Networks - genetics Genes Humans Male NAV1.8 Voltage-Gated Sodium Channel - genetics Neuralgia Neuralgia - genetics Neuralgia - pathology Neuralgia - therapy Neurological diseases neuropathic pain Pain Protein Interaction Maps - genetics protein‐interaction network SCN10A Signal transduction Signal Transduction - genetics Somatostatin - genetics Spinal Cord - metabolism Spinal Cord - pathology Spinal nerves SST Target recognition Therapeutic applications
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