Targeting the Cutaneous Microbiota in Atopic Dermatitis by Coal Tar via AHR-Dependent Induction of Antimicrobial Peptides

Skin colonization by Staphylococcus aureus and its relative abundance is associated with atopic dermatitis (AD) disease severity and treatment response. Low levels of antimicrobial peptides in AD skin may be related to the microbial dysbiosis. Therapeutic targeting of the skin microbiome and antimic...

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Veröffentlicht in:	Journal of investigative dermatology 2020-02, Vol.140 (2), p.415-424.e10
Hauptverfasser:	Smits, Jos P.H., Ederveen, Thomas H.A., Rikken, Gijs, van den Brink, Noa J.M., van Vlijmen-Willems, Ivonne M.J.J., Boekhorst, Jos, Kamsteeg, Marijke, Schalkwijk, Joost, van Hijum, Sacha A.F.T., Zeeuwen, Patrick L.J.M., van den Bogaard, Ellen H.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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