Effect of Cell-Penetrating Arginine Peptide on Interaction of Photosensitizer Chlorin e6 Incorporated into Phospholipid Nanoparticles with Tumor Cells

We studied the possibility of increasing the efficiency of photodynamic therapy by improving delivery of photosensitizers chlorin e6 into tumor cells. Previous studies showed that incorporation of chlorin e6 onto phospholipid nanoparticles with a diameter

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2019-07, Vol.167 (3), p.347-350
Hauptverfasser:	Kostryukova, L. V., Korotkevich, E. I., Morozevich, G. E., Kolesanova, E. F., Mel’nikova, M. V., Filatova, Yu. V., Torkhovskaya, T. I., Prozorovskii, V. N., Tikhonova, E. G., Ipatova, O. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Arginine Arginine - chemistry Biomedical and Life Sciences Biomedicine Cancer Cell Biology Cell Line, Tumor Cell-Penetrating Peptides - chemistry Cell-Penetrating Peptides - pharmacology Cytotoxicity Endocytosis Endocytosis - physiology Health aspects Hep G2 Cells Humans Internal Medicine Internalization Laboratory Medicine Nanoparticles Nanoparticles - chemistry Oligopeptides - chemistry Oligopeptides - pharmacology Pathology Peptide Fragments - chemistry Peptides Phospholipids Phospholipids - chemistry Photochemotherapy Photochemotherapy - methods Photodynamic therapy Pinocytosis - physiology Porphyrins - chemistry Porphyrins - pharmacology Protein Transport - drug effects Tumor cells Tumors
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Zusammenfassung:	We studied the possibility of increasing the efficiency of photodynamic therapy by improving delivery of photosensitizers chlorin e6 into tumor cells. Previous studies showed that incorporation of chlorin e6 onto phospholipid nanoparticles with a diameter
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-019-04524-x