The predictive value of red cell distribution width on erectile dysfunction
Red cell distribution width (RDW), one of the biomarkers used to measure vascular ageing, is known to correspond with cardiovascular diseases. As coronary artery disease and erectile dysfunction (ED) are both caused by the same shared pathophysiology, in this study, we compared the RDW values of men...
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Veröffentlicht in: | Andrologia 2019-11, Vol.51 (10), p.e13374-n/a |
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description | Red cell distribution width (RDW), one of the biomarkers used to measure vascular ageing, is known to correspond with cardiovascular diseases. As coronary artery disease and erectile dysfunction (ED) are both caused by the same shared pathophysiology, in this study, we compared the RDW values of men diagnosed with ED and those of healthy controls. Ninety‐nine patients who were diagnosed with ED were included in the study. The control group consists of 100 men who presented to our outpatient clinic. Patients' fasting blood glucose, triglyceride, total cholesterol and LDL cholesterol levels were significantly higher in men diagnosed with ED. While the mean RDW value was 13.49 ± 1.52 in men with ED, it was 12.91 ± 1.13 in the control group. When RDW values were compared between the two groups, the RDW values of men with ED were found to be statistically significantly higher. Multivariate analyses showed that only the patients' body mass index, fasting blood sugar, triglyceride (TG), low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol levels (HDL‐C), TG/HDL‐C ratio and RDW levels' relationship with ED was statistically significant. Although some studies have shown that RDW may be related to some diseases such as cardiovascular diseases and cancer, this appears to be the first study demonstrating a relationship between RDW and ED. RDW can be utilised as a predictor for the determination of the presence and monitoring of the severity of ED. |
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As coronary artery disease and erectile dysfunction (ED) are both caused by the same shared pathophysiology, in this study, we compared the RDW values of men diagnosed with ED and those of healthy controls. Ninety‐nine patients who were diagnosed with ED were included in the study. The control group consists of 100 men who presented to our outpatient clinic. Patients' fasting blood glucose, triglyceride, total cholesterol and LDL cholesterol levels were significantly higher in men diagnosed with ED. While the mean RDW value was 13.49 ± 1.52 in men with ED, it was 12.91 ± 1.13 in the control group. When RDW values were compared between the two groups, the RDW values of men with ED were found to be statistically significantly higher. Multivariate analyses showed that only the patients' body mass index, fasting blood sugar, triglyceride (TG), low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol levels (HDL‐C), TG/HDL‐C ratio and RDW levels' relationship with ED was statistically significant. Although some studies have shown that RDW may be related to some diseases such as cardiovascular diseases and cancer, this appears to be the first study demonstrating a relationship between RDW and ED. RDW can be utilised as a predictor for the determination of the presence and monitoring of the severity of ED.</description><identifier>ISSN: 0303-4569</identifier><identifier>EISSN: 1439-0272</identifier><identifier>DOI: 10.1111/and.13374</identifier><identifier>PMID: 31347716</identifier><language>eng</language><publisher>Germany: Wiley Subscription Services, Inc</publisher><subject>Adult ; Aging ; Biomarkers ; Body mass index ; Cardiovascular disease ; Cardiovascular diseases ; Case-Control Studies ; Cholesterol ; Coronary artery ; Coronary Artery Disease - blood ; Coronary Artery Disease - complications ; Erectile dysfunction ; Erectile Dysfunction - blood ; Erectile Dysfunction - diagnosis ; Erectile Dysfunction - etiology ; Erythrocyte Indices ; Fasting ; Feasibility Studies ; Health risk assessment ; Heart diseases ; High density lipoprotein ; Humans ; IIEF‐5 ; Laboratory testing ; Low density lipoprotein ; Male ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; red cell distribution ; Severity of Illness Index ; Statistical analysis ; TG/HDL ratio</subject><ispartof>Andrologia, 2019-11, Vol.51 (10), p.e13374-n/a</ispartof><rights>2019 Blackwell Verlag GmbH</rights><rights>2019 Blackwell Verlag GmbH.</rights><rights>Copyright © 2019 Blackwell Verlag GmbH</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3884-e59f501d345b29f9c0e23c9669bd0c4f9e6ee2c6679cf034370a85654db89a493</citedby><cites>FETCH-LOGICAL-c3884-e59f501d345b29f9c0e23c9669bd0c4f9e6ee2c6679cf034370a85654db89a493</cites><orcidid>0000-0002-7459-584X ; 0000-0001-9115-7203 ; 0000-0002-4674-908X ; 0000-0002-6612-0166</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fand.13374$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fand.13374$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31347716$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dursun, Murat</creatorcontrib><creatorcontrib>Cimen, Serhan</creatorcontrib><creatorcontrib>Sulukaya, Muhammed</creatorcontrib><creatorcontrib>Bugday, Muhammed Serdar</creatorcontrib><creatorcontrib>Besiroglu, Huseyin</creatorcontrib><title>The predictive value of red cell distribution width on erectile dysfunction</title><title>Andrologia</title><addtitle>Andrologia</addtitle><description>Red cell distribution width (RDW), one of the biomarkers used to measure vascular ageing, is known to correspond with cardiovascular diseases. As coronary artery disease and erectile dysfunction (ED) are both caused by the same shared pathophysiology, in this study, we compared the RDW values of men diagnosed with ED and those of healthy controls. Ninety‐nine patients who were diagnosed with ED were included in the study. The control group consists of 100 men who presented to our outpatient clinic. Patients' fasting blood glucose, triglyceride, total cholesterol and LDL cholesterol levels were significantly higher in men diagnosed with ED. While the mean RDW value was 13.49 ± 1.52 in men with ED, it was 12.91 ± 1.13 in the control group. When RDW values were compared between the two groups, the RDW values of men with ED were found to be statistically significantly higher. Multivariate analyses showed that only the patients' body mass index, fasting blood sugar, triglyceride (TG), low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol levels (HDL‐C), TG/HDL‐C ratio and RDW levels' relationship with ED was statistically significant. Although some studies have shown that RDW may be related to some diseases such as cardiovascular diseases and cancer, this appears to be the first study demonstrating a relationship between RDW and ED. RDW can be utilised as a predictor for the determination of the presence and monitoring of the severity of ED.</description><subject>Adult</subject><subject>Aging</subject><subject>Biomarkers</subject><subject>Body mass index</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Case-Control Studies</subject><subject>Cholesterol</subject><subject>Coronary artery</subject><subject>Coronary Artery Disease - blood</subject><subject>Coronary Artery Disease - complications</subject><subject>Erectile dysfunction</subject><subject>Erectile Dysfunction - blood</subject><subject>Erectile Dysfunction - diagnosis</subject><subject>Erectile Dysfunction - etiology</subject><subject>Erythrocyte Indices</subject><subject>Fasting</subject><subject>Feasibility Studies</subject><subject>Health risk assessment</subject><subject>Heart diseases</subject><subject>High density lipoprotein</subject><subject>Humans</subject><subject>IIEF‐5</subject><subject>Laboratory testing</subject><subject>Low density lipoprotein</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>red cell distribution</subject><subject>Severity of Illness Index</subject><subject>Statistical analysis</subject><subject>TG/HDL ratio</subject><issn>0303-4569</issn><issn>1439-0272</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kD1PwzAQhi0EolXpwB9AllhgSOvYjh2PVfkUFSxlthL7oqZKk2InrfrvcT9gQOKWs-4evzo9CF3HZBSHGme1HcWMSX6G-jFnKiJU0nPUJ4ywiCdC9dDQ-yUJxRMpOb9EPRYzLmUs-uhtvgC8dmBL05YbwJus6gA3BQ4jbKCqsC1968q8a8umxtvStgscHuAgfKgA250vutrst1foosgqD8NTH6DPp8f59CWafTy_TiezyLA05REkqkhIbBlPcqoKZQhQZpQQKrfE8EKBAKBGCKlMQRhnkmRpIhJu81RlXLEBujvmrl3z1YFv9ar0-1uzGprOa0pFIrlQlAX09g-6bDpXh-s0ZUTJVIlD4P2RMq7x3kGh165cZW6nY6L3knWQrA-SA3tzSuzyFdhf8kdpAMZHYBv07P5P0pP3h2PkN54ChEs</recordid><startdate>201911</startdate><enddate>201911</enddate><creator>Dursun, Murat</creator><creator>Cimen, Serhan</creator><creator>Sulukaya, Muhammed</creator><creator>Bugday, Muhammed Serdar</creator><creator>Besiroglu, Huseyin</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7459-584X</orcidid><orcidid>https://orcid.org/0000-0001-9115-7203</orcidid><orcidid>https://orcid.org/0000-0002-4674-908X</orcidid><orcidid>https://orcid.org/0000-0002-6612-0166</orcidid></search><sort><creationdate>201911</creationdate><title>The predictive value of red cell distribution width on erectile dysfunction</title><author>Dursun, Murat ; Cimen, Serhan ; Sulukaya, Muhammed ; Bugday, Muhammed Serdar ; Besiroglu, Huseyin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3884-e59f501d345b29f9c0e23c9669bd0c4f9e6ee2c6679cf034370a85654db89a493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Aging</topic><topic>Biomarkers</topic><topic>Body mass index</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Case-Control Studies</topic><topic>Cholesterol</topic><topic>Coronary artery</topic><topic>Coronary Artery Disease - blood</topic><topic>Coronary Artery Disease - complications</topic><topic>Erectile dysfunction</topic><topic>Erectile Dysfunction - blood</topic><topic>Erectile Dysfunction - diagnosis</topic><topic>Erectile Dysfunction - etiology</topic><topic>Erythrocyte Indices</topic><topic>Fasting</topic><topic>Feasibility Studies</topic><topic>Health risk assessment</topic><topic>Heart diseases</topic><topic>High density lipoprotein</topic><topic>Humans</topic><topic>IIEF‐5</topic><topic>Laboratory testing</topic><topic>Low density lipoprotein</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>red cell distribution</topic><topic>Severity of Illness Index</topic><topic>Statistical analysis</topic><topic>TG/HDL ratio</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dursun, Murat</creatorcontrib><creatorcontrib>Cimen, Serhan</creatorcontrib><creatorcontrib>Sulukaya, Muhammed</creatorcontrib><creatorcontrib>Bugday, Muhammed Serdar</creatorcontrib><creatorcontrib>Besiroglu, Huseyin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Andrologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dursun, Murat</au><au>Cimen, Serhan</au><au>Sulukaya, Muhammed</au><au>Bugday, Muhammed Serdar</au><au>Besiroglu, Huseyin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The predictive value of red cell distribution width on erectile dysfunction</atitle><jtitle>Andrologia</jtitle><addtitle>Andrologia</addtitle><date>2019-11</date><risdate>2019</risdate><volume>51</volume><issue>10</issue><spage>e13374</spage><epage>n/a</epage><pages>e13374-n/a</pages><issn>0303-4569</issn><eissn>1439-0272</eissn><abstract>Red cell distribution width (RDW), one of the biomarkers used to measure vascular ageing, is known to correspond with cardiovascular diseases. As coronary artery disease and erectile dysfunction (ED) are both caused by the same shared pathophysiology, in this study, we compared the RDW values of men diagnosed with ED and those of healthy controls. Ninety‐nine patients who were diagnosed with ED were included in the study. The control group consists of 100 men who presented to our outpatient clinic. Patients' fasting blood glucose, triglyceride, total cholesterol and LDL cholesterol levels were significantly higher in men diagnosed with ED. While the mean RDW value was 13.49 ± 1.52 in men with ED, it was 12.91 ± 1.13 in the control group. When RDW values were compared between the two groups, the RDW values of men with ED were found to be statistically significantly higher. Multivariate analyses showed that only the patients' body mass index, fasting blood sugar, triglyceride (TG), low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol levels (HDL‐C), TG/HDL‐C ratio and RDW levels' relationship with ED was statistically significant. Although some studies have shown that RDW may be related to some diseases such as cardiovascular diseases and cancer, this appears to be the first study demonstrating a relationship between RDW and ED. 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subjects | Adult Aging Biomarkers Body mass index Cardiovascular disease Cardiovascular diseases Case-Control Studies Cholesterol Coronary artery Coronary Artery Disease - blood Coronary Artery Disease - complications Erectile dysfunction Erectile Dysfunction - blood Erectile Dysfunction - diagnosis Erectile Dysfunction - etiology Erythrocyte Indices Fasting Feasibility Studies Health risk assessment Heart diseases High density lipoprotein Humans IIEF‐5 Laboratory testing Low density lipoprotein Male Middle Aged Predictive Value of Tests Prospective Studies red cell distribution Severity of Illness Index Statistical analysis TG/HDL ratio |
title | The predictive value of red cell distribution width on erectile dysfunction |
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