Epithelial‐to‐mesenchymal transition and keratinocyte differentiation in equine experimental body and limb wounds healing by second intention

Background The re‐epithelialization process in equine wound healing is incompletely described. For epithelial cells to migrate during embryogenesis they undergo epithelial‐to‐mesenchymal transition (EMT); this phenotypic transition occurs during wound healing in humans and rodents, but it has not be...

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Veröffentlicht in:	Veterinary dermatology 2019-10, Vol.30 (5), p.417-e126
Hauptverfasser:	Jørgensen, Elin, Pirone, Andrea, Jacobsen, Stine, Miragliotta, Vincenzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - metabolism Biopsy Cadherins - genetics Cadherins - metabolism Cell Differentiation - physiology Cytokeratin Embryogenesis Embryonic growth stage Epithelial cells Epithelial-Mesenchymal Transition Epithelium Extremities - injuries Gene Expression Regulation Genetic transformation Horses Horses - injuries Immunohistochemistry Indication Investigations Keratinocytes - physiology Keratins - genetics Keratins - metabolism Membrane Proteins - genetics Membrane Proteins - metabolism Mesenchyme Migration Peroxisome proliferator-activated receptors PPAR alpha - genetics PPAR alpha - metabolism Rodents Skin Wound healing Wound Healing - physiology
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