Substrate stiffness directs diverging vascular fates

[Display omitted] Embryonic stem cells (ESC) are excellent cell culture systems for elucidating developmental signals that may be part of the stem cell niche. Although stem cells are traditionally induced using predominately soluble signals, the mechanical environment of the niche can also play a ro...

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Veröffentlicht in:	Acta biomaterialia 2019-09, Vol.96, p.321-329
Hauptverfasser:	Wong, Lian, Kumar, Ashwath, Gabela-Zuniga, Basia, Chua, Je, Singh, Gagandip, Happe, Cassandra L., Engler, Adam J., Fan, Yuhong, McCloskey, Kara E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture Cell differentiation Cell lines Differentiation Embryo cells Endothelial cells Gene expression Hydrogels Matrix stiffness Muscles Organic chemistry Polyacrylamide Populations Progenitor cells Smooth muscle Smooth muscle cells Stem cells Stiffness Substrates Tissue engineering Vascular progenitor cells
Online-Zugang:	Volltext
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