Chronic lymphocytic leukemia patients with HLA-B27 referred for allogeneic hematopoietic stem cell transplantation do not have worse outcomes: Results of a population-based case series analysis in British Columbia, Canada

•outcomes were not different for HLA-B27 CLL patients with/without spondyloarthritis.•HLA-B27 does not influence clinical course of CLL patients for marrow transplant.•Routine HLA-B27 testing in CLL/SLL not warranted. Human leukocyte antigen B27 (HLA-B27), associated with spondyloarthritis, was sugg...

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Veröffentlicht in:	Leukemia research 2019-09, Vol.84, p.106193-106193, Article 106193
Hauptverfasser:	Huang, Steven J., Chan, Jonathan, Bruyère, Helene, Allan, Lenka L., Gerrie, Alina S., Toze, Cynthia L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Ankylosing spondylitis British Columbia - epidemiology Case series Case-Control Studies CLL Comorbidity Female Hematopoietic Stem Cell Transplantation HLA-B27 HLA-B27 Antigen - genetics Humans Leukemia, Lymphocytic, Chronic, B-Cell - epidemiology Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Lymphocytic, Chronic, B-Cell - mortality Leukemia, Lymphocytic, Chronic, B-Cell - therapy Male Middle Aged Outcome Prognosis Public Health Surveillance Spondyloarthritis Survival Analysis Transplantation, Homologous Treatment Outcome
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