Syndecan-1 facilitates breast cancer metastasis to the brain

Purpose Although survival rates for patients with localized breast cancer have increased, patients with metastatic breast cancer still have poor prognosis. Understanding key factors involved in promoting breast cancer metastasis is imperative for better treatments. In this study, we investigated the...

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Veröffentlicht in:	Breast cancer research and treatment 2019-11, Vol.178 (1), p.35-49
Hauptverfasser:	Sayyad, Megan R., Puchalapalli, Madhavi, Vergara, Natasha G., Wangensteen, Sierra Mosticone, Moore, Melvin, Mu, Liang, Edwards, Chevaunne, Anderson, Aubree, Kall, Stefanie, Sullivan, Megan, Dozmorov, Mikhail, Singh, Jaime, Idowu, Michael O., Koblinski, Jennifer E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Astrocytes Blood-brain barrier Blood-Brain Barrier - immunology Brain cancer Brain Neoplasms - genetics Brain Neoplasms - metabolism Brain Neoplasms - secondary Breast cancer Cancer research Carcinoma Cell adhesion & migration Cell Line, Tumor Cell migration Cell Movement Chemokines Cytokines Cytokines - metabolism Development and progression Endothelial cells Ethylenediaminetetraacetic acid Female Gene Expression Regulation, Neoplastic Gene Silencing Humans Mammary gland Medical prognosis Medicine Medicine & Public Health Metastases Metastasis Mice Neoplasm Transplantation Oncology Preclinical Study Prognosis Secretome Syndecan Syndecan-1 - genetics Syndecan-1 - metabolism Tissue Array Analysis Triple Negative Breast Neoplasms - genetics Triple Negative Breast Neoplasms - metabolism Up-Regulation
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