Protein engineering for bioreduction of carboxylic acids

•Wildtype and engineered carboxylic acid reductases expand the bioorganic synthesis toolbox.•Protein engineering unravels key catalytic residues in carboxylic acid reductases.•Protein engineering consolidates mechanistic understanding as well as structure-function relationship of carboxylic acid red...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of biotechnology 2019-09, Vol.303, p.53-64
Hauptverfasser:	Tee, Kang Lan, Xu, Jian-He, Wong, Tuck Seng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Aldehyde Bacterial Proteins - genetics Bacterial Proteins - metabolism Biocatalysis Bioreduction Carboxylate reductase Carboxylic acid Carboxylic acid reductase Carboxylic Acids - metabolism Fungal Proteins - genetics Fungal Proteins - metabolism NADP - metabolism Nonribosomal peptide synthetase Oxidoreductases - genetics Oxidoreductases - metabolism Protein Engineering - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!