Kir7.1 inwardly rectifying K+ channel is expressed in ciliary body non pigment epithelial cells and might contribute to intraocular pressure regulation

Inwardly rectifying K+ channel Kir7.1 is expressed in epithelia where it shares membrane localisation with the Na+/K+-pump. The ciliary body epithelium (CBE) of the eye is a determinant of intraocular pressure (IOP) through NaCl-driven fluid secretion of aqueous humour. In the present study we explo...

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Veröffentlicht in:	Experimental eye research 2019-09, Vol.186, p.107723-107723, Article 107723
Hauptverfasser:	Burgos, Johanna, Villanueva, Sandra, Ojeda, Margarita, Cornejo, Isabel, Cid, L. Pablo, Sepúlveda, Francisco V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aqueous humour production Ciliary body Ciliary Body - metabolism Epithelial Cells - metabolism Epithelial fluid transport Intraocular Pressure - physiology K+ channel Mice Mice, Inbred C57BL Mice, Knockout Non pigmented epithelial cells Potassium Channels, Inwardly Rectifying - metabolism
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