Resveratrol Promotes in vitro Differentiation of Osteoblastic MC3T3-E1 Cells via Potentiation of the Calcineurin/NFATc1 Signaling Pathway

Resveratrol has been shown to stimulate differentiation of osteoblastic MC3T3-E1 cells in vitro ; however, the mechanisms underlying the anabolic effect of resveratrol on osteoblasts remain largely unknown. Our study was aimed to investigate the molecular mechanism of resveratrol-induced differentia...

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Veröffentlicht in:	Biochemistry (Moscow) 2019-06, Vol.84 (6), p.686-692
Hauptverfasser:	Huang, Y., Huo, J., Liu, F. Q., Liu, J., Zhang, X. J., Guo, C. H., Song, L. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biochemistry Biocompatibility Biomedical and Life Sciences Biomedical materials Biomedicine Bioorganic Chemistry Calcineurin Cbfa-1 protein Cell proliferation Cellular signal transduction Comparative analysis Cyclosporins Differentiation Gene expression Genes Kinases Life Sciences Microbiology NF-AT protein Nuclei (cytology) Osteoblastogenesis Osteoblasts Osteosis Polymerase chain reaction Proteins Resveratrol Signal transduction Signaling
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