Systemic Succinate, Hypoxia-Inducible Factor-1 Alpha, and IL-1β Gene Expression in Autosomal Dominant Polycystic Kidney Disease with and without Hypertension

Background and Objectives: Cyst pressure induces renin-angiotensin-aldosterone system activation and kidney hypoxia in autosomal dominant polycystic kidney disease (ADPKD). Lipopolysaccharide-induced Toll-like receptor activation causes metabolic disturbances that are triggered by increased succinat...

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Veröffentlicht in:Cardiorenal medicine 2019, Vol.9 (6), p.370-381
Hauptverfasser: Kocyigit, Ismail, Taheri, Serpil, Eroglu, Eray, Sener, Elif Funda, Zararsız, Gokmen, Uzun, Ilknur, Tufan, Esra, Mehmetbeyoglu, Ecmel, Korkmaz Bayramov, Kezban, Sipahioglu, Murat Hayri, Ozkul, Yusuf, Tokgoz, Bulent, Oymak, Oktay, Axelsson, Jonas
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Sprache:eng
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