Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia

For the treatment of patients with prediabetes or diabetes, clinical evidence has emerged that β-cell function can be restored by glucose-lowering therapeutic strategies. However, little is known about the molecular mechanisms underlying this functional adaptive behavior of the pancreatic β-cell. Th...

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Veröffentlicht in:Journal of proteome research 2019-09, Vol.18 (9), p.3245-3258
Hauptverfasser: Kang, Taewook, Boland, Brandon B, Alarcon, Cristina, Grimsby, Joseph S, Rhodes, Christopher J, Larsen, Martin R
Format: Artikel
Sprache:eng
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