A model‐based framework for parallel scale‐down fed‐batch cultivations in mini‐bioreactors for accelerated phenotyping

Concentration gradients that occur in large industrial‐scale bioreactors due to mass transfer limitations have significant effects on process efficiency. Hence, it is desirable to investigate the response of strains to such heterogeneities to reduce the risk of failure during process scale‐up. Altho...

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Veröffentlicht in:Biotechnology and bioengineering 2019-11, Vol.116 (11), p.2906-2918
Hauptverfasser: Anane, Emmanuel, García, Ángel Córcoles, Haby, Benjamin, Hans, Sebastian, Krausch, Niels, Krewinkel, Manuel, Hauptmann, Peter, Neubauer, Peter, Cruz Bournazou, Mariano Nicolas
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Sprache:eng
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