Tumor Suppressor p53-Mediated Structural Reorganization of the Transcriptional Coactivator p300

Transcriptional coactivator p300, a critical player in eukaryotic gene regulation, primarily functions as a histone acetyltransferase (HAT). It is also an important player in acetylation of a number of nonhistone proteins, p53 being the most prominent one. Recruitment of p300 to p53 is pivotal in th...

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Veröffentlicht in:	Biochemistry (Easton) 2019-08, Vol.58 (32), p.3434-3443
Hauptverfasser:	Ghosh, Raka, Kaypee, Stephanie, Shasmal, Manidip, Kundu, Tapas K, Roy, Siddhartha, Sengupta, Jayati
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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