CD4+ T cell signatures in HIV infection
Analysis of the whole-genome transcriptional activity of HIV-specific CD4 + T cells demonstrates distinct profiles associated with natural control of HIV replication, as well as dysfunctional phenotypes that persist even after effective antiretroviral therapy.
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| Veröffentlicht in: | Nature immunology 2019-08, Vol.20 (8), p.948-950 |
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| container_end_page | 950 |
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| container_title | Nature immunology |
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| creator | Gubser, Celine Pitman, Matthew C Lewin, Sharon R. |
| description | Analysis of the whole-genome transcriptional activity of HIV-specific CD4
+
T cells demonstrates distinct profiles associated with natural control of HIV replication, as well as dysfunctional phenotypes that persist even after effective antiretroviral therapy. |
| doi_str_mv | 10.1038/s41590-019-0447-5 |
| format | Article |
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| subjects | 631/250/1619/554/1898/1270 631/250/2499 631/250/255/1901 631/326/596/2558 Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Biomedical and Life Sciences Biomedicine CD4 antigen Genomes HIV Human immunodeficiency virus Immunology Infectious Diseases Lymphocytes Lymphocytes T News & Views news-and-views Phenotypes Transcription |
| title | CD4+ T cell signatures in HIV infection |
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