Exposure to intermittent hypoxia inhibits allergic airway inflammation in a murine model of asthma

Purpose Obesity increases the severity of asthma, and patients with severe asthma are often complicated with obstructive sleep apnea syndrome (OSAS), a concomitant disease of obesity. We investigated whether intermittent hypoxia (IH), which is a physiological feature of OSAS, modifies allergic airwa...

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Veröffentlicht in:	Sleep & breathing 2020-06, Vol.24 (2), p.523-532
Hauptverfasser:	Ohta, Shin, Tanaka, Akihiko, Jinno, Megumi, Hirai, Kuniaki, Miyata, Yoshito, Yamaguchi, Munehiro, Homma, Tetsuya, Muramoto, Mayumi, Watanabe, Yoshio, Suzuki, Shintaro, Yokoe, Takuya, Sagara, Hironori
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Animal models Animals Apnea Asthma Asthma - physiopathology Dentistry Disease Models, Animal Female Hyperplasia Hypoxia Hypoxia - physiopathology Inflammation Inflammation - physiopathology Interleukin 13 Interleukin 5 Internal Medicine Leukocytes (eosinophilic) Medicine Medicine & Public Health Metaplasia Mice Mice, Inbred BALB C Neurology Obesity Otorhinolaryngology Ovalbumin Pediatrics Pneumology/Respiratory System Respiratory Hypersensitivity - physiopathology Respiratory tract Respiratory tract diseases Sleep Sleep Apnea, Obstructive - physiopathology Sleep Breathing Physiology and Disorders • Original Article Sleep disorders
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