Study on Diagnostic Values of Astrocyte Elevated Gene 1 (AEG-1) and Glypican 3 (GPC-3) in Hepatocellular Carcinoma

Abstract Objectives To investigate the diagnostic potential of AEG-1 and GPC-3 in hepatocellular carcinoma (HCC). Methods AEG-1 and GPC-3 immunohistochemistry were performed on HCC, adjacent nontumor tissue (ANT), and dysplastic nodules (DN). Results H score of AEG-1 or GPC-3 in HCC was significantl...

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Veröffentlicht in:	American journal of clinical pathology 2019-10, Vol.152 (5), p.647-655
Hauptverfasser:	Cao, Wenqing, Sharma, Meenal, Imam, Rami, Yu, Jiangzhou
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Aged Biomarkers, Tumor - analysis Carcinoma, Hepatocellular - chemistry Carcinoma, Hepatocellular - diagnosis Female Gene Expression Glypicans - analysis Glypicans - genetics Heparan sulfate proteoglycans Hepatocellular carcinoma Humans Immunohistochemistry Liver cancer Liver Neoplasms - chemistry Liver Neoplasms - diagnosis Male Medical diagnosis Membrane Proteins - analysis Membrane Proteins - genetics Middle Aged Nodules RNA-Binding Proteins - analysis RNA-Binding Proteins - genetics Sensitivity and Specificity
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