Mimicking the endothelial glycocalyx through the supramolecular presentation of hyaluronan on patterned surfaces

The glycocalyx is the immediate pericellular matrix that surrounds many cell types, including endothelial cells (ECs), and is typically composed of glycans (glycosaminoglycans, proteoglycans, and glycoproteins). The endothelial glycocalyx is rich in hyaluronic acid (HA), which plays an important rol...

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Veröffentlicht in:	Faraday discussions 2019-10, Vol.219, p.168-182
Hauptverfasser:	Pang, Xinqing, Li, Weiqi, Landwehr, Eliane, Yuan, Yichen, Wang, Wen, Azevedo, Helena S
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Biocompatible Materials - chemistry Bioprinting Cell Adhesion Cell Movement Contact angle Control Endothelial cells Endothelial Cells - chemistry Endothelial Cells - cytology Fluorescence Glycocalyx - chemistry Glycosaminoglycans Gold Gold - chemistry Human Umbilical Vein Endothelial Cells Humans Hyaluronic acid Hyaluronic Acid - chemistry Low molecular weights Maintenance Microbalances Peptides Peptides - chemistry Phages Photoelectrons Proteoglycans Quartz crystals Self-assembled monolayers Self-assembly Substrates Sulfhydryl Compounds - chemistry Surface Properties X ray photoelectron spectroscopy
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