Molecular markers derived from ovarian cancer and its correlation with the types of oviductal epithelial lesions
To explore the role of P53, pairing box gene 8 antibody (PAX8), and calcium omentum protein (Calretinin) in the origin of epithelial ovarian cancer. Methods: A total of 63 tissue samples of ovarian tumor and fallopian tubes were collected. Immunohistochemistry methods were used to analyze the expre...
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| Veröffentlicht in: | Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban 2019-05, Vol.44 (5), p.528-534 |
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| container_title | Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban |
| container_volume | 44 |
| creator | Yuan, Yishu Zhu, Wei Gong, Guanghui Jiang, Jing Wang, Yixuan Wu, Xiaoying |
| description | To explore the role of P53, pairing box gene 8 antibody (PAX8), and calcium omentum protein (Calretinin) in the origin of epithelial ovarian cancer.
Methods: A total of 63 tissue samples of ovarian tumor and fallopian tubes were collected. Immunohistochemistry methods were used to analyze the expression of P53, PAX8, and Calretinin. The relationship between these protein levels and the classification of ovarian tumors was evaluated.
Results: In epithelial ovarian cancer, the P53 or PAX8 was correlated with the occurrence of high-grade carcinoma, while the calretinin was correlated with the occurrence of low-grade carcinoma (P |
| doi_str_mv | 10.11817/j.issn.1672-7347.2019.05.009 |
| format | Article |
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Methods: A total of 63 tissue samples of ovarian tumor and fallopian tubes were collected. Immunohistochemistry methods were used to analyze the expression of P53, PAX8, and Calretinin. The relationship between these protein levels and the classification of ovarian tumors was evaluated.
Results: In epithelial ovarian cancer, the P53 or PAX8 was correlated with the occurrence of high-grade carcinoma, while the calretinin was correlated with the occurrence of low-grade carcinoma (P<0.05). The combination of PAX8 with Calretinin was correlated with the grade of ovarian tumor (P<0.05). The combination of P53 with Calretinin was correlated with the grade of tumor (P<0.05). The combination of P53 with PAX8 was correlated with the grade of tumor (P<0.05). The expression of P53 in fallopian tubes was correlated with the malignant degree of epithelial ovarian cancer (P<</description><identifier>ISSN: 1672-7347</identifier><identifier>DOI: 10.11817/j.issn.1672-7347.2019.05.009</identifier><identifier>PMID: 31303616</identifier><language>chi</language><publisher>China</publisher><subject>Carcinoma, Ovarian Epithelial ; Epithelium ; Fallopian Tubes ; Female ; Humans ; Ovarian Neoplasms ; PAX8 Transcription Factor</subject><ispartof>Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban, 2019-05, Vol.44 (5), p.528-534</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31303616$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yuan, Yishu</creatorcontrib><creatorcontrib>Zhu, Wei</creatorcontrib><creatorcontrib>Gong, Guanghui</creatorcontrib><creatorcontrib>Jiang, Jing</creatorcontrib><creatorcontrib>Wang, Yixuan</creatorcontrib><creatorcontrib>Wu, Xiaoying</creatorcontrib><title>Molecular markers derived from ovarian cancer and its correlation with the types of oviductal epithelial lesions</title><title>Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban</title><addtitle>Zhong Nan Da Xue Xue Bao Yi Xue Ban</addtitle><description>To explore the role of P53, pairing box gene 8 antibody (PAX8), and calcium omentum protein (Calretinin) in the origin of epithelial ovarian cancer.
Methods: A total of 63 tissue samples of ovarian tumor and fallopian tubes were collected. Immunohistochemistry methods were used to analyze the expression of P53, PAX8, and Calretinin. The relationship between these protein levels and the classification of ovarian tumors was evaluated.
Results: In epithelial ovarian cancer, the P53 or PAX8 was correlated with the occurrence of high-grade carcinoma, while the calretinin was correlated with the occurrence of low-grade carcinoma (P<0.05). The combination of PAX8 with Calretinin was correlated with the grade of ovarian tumor (P<0.05). The combination of P53 with Calretinin was correlated with the grade of tumor (P<0.05). The combination of P53 with PAX8 was correlated with the grade of tumor (P<0.05). The expression of P53 in fallopian tubes was correlated with the malignant degree of epithelial ovarian cancer (P<</description><subject>Carcinoma, Ovarian Epithelial</subject><subject>Epithelium</subject><subject>Fallopian Tubes</subject><subject>Female</subject><subject>Humans</subject><subject>Ovarian Neoplasms</subject><subject>PAX8 Transcription Factor</subject><issn>1672-7347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD9PwzAUxD2AaFX6FZAXJJYEO44de0QV_6Qilu6RY7-oBjcOtlPUb08kCtM93f3eDYfQLSUlpZI29x-lS2koqWiqomF1U1aEqpLwkhB1gZb__gKtU3Ld7CrFhGyu0IJRRpigYonGt-DBTF5HfNDxE2LCFqI7gsV9DAccjjo6PWCjBwMR68FilxM2IUbwOrsw4G-X9zjvAefTCAmHfn5ydjJZewzjHIJ38-khzXS6Rpe99gnWZ12h3dPjbvNSbN-fXzcP22LkQhQgFLNSk57QTtadVKyvLQAlNVAlhQQDltOag-64tLKBhhpiRAW0AiV5x1bo7rd2jOFrgpTbg0sGvNcDhCm1VcUl5RVXckZvzujUHcC2Y3TzFKf2byT2A3jabdI</recordid><startdate>20190528</startdate><enddate>20190528</enddate><creator>Yuan, Yishu</creator><creator>Zhu, Wei</creator><creator>Gong, Guanghui</creator><creator>Jiang, Jing</creator><creator>Wang, Yixuan</creator><creator>Wu, Xiaoying</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20190528</creationdate><title>Molecular markers derived from ovarian cancer and its correlation with the types of oviductal epithelial lesions</title><author>Yuan, Yishu ; Zhu, Wei ; Gong, Guanghui ; Jiang, Jing ; Wang, Yixuan ; Wu, Xiaoying</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p566-e693d8a0f01b84b893f4dee104e19868eced5145eab58d87e71c0c62e12e985b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2019</creationdate><topic>Carcinoma, Ovarian Epithelial</topic><topic>Epithelium</topic><topic>Fallopian Tubes</topic><topic>Female</topic><topic>Humans</topic><topic>Ovarian Neoplasms</topic><topic>PAX8 Transcription Factor</topic><toplevel>online_resources</toplevel><creatorcontrib>Yuan, Yishu</creatorcontrib><creatorcontrib>Zhu, Wei</creatorcontrib><creatorcontrib>Gong, Guanghui</creatorcontrib><creatorcontrib>Jiang, Jing</creatorcontrib><creatorcontrib>Wang, Yixuan</creatorcontrib><creatorcontrib>Wu, Xiaoying</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yuan, Yishu</au><au>Zhu, Wei</au><au>Gong, Guanghui</au><au>Jiang, Jing</au><au>Wang, Yixuan</au><au>Wu, Xiaoying</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Molecular markers derived from ovarian cancer and its correlation with the types of oviductal epithelial lesions</atitle><jtitle>Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban</jtitle><addtitle>Zhong Nan Da Xue Xue Bao Yi Xue Ban</addtitle><date>2019-05-28</date><risdate>2019</risdate><volume>44</volume><issue>5</issue><spage>528</spage><epage>534</epage><pages>528-534</pages><issn>1672-7347</issn><abstract>To explore the role of P53, pairing box gene 8 antibody (PAX8), and calcium omentum protein (Calretinin) in the origin of epithelial ovarian cancer.
Methods: A total of 63 tissue samples of ovarian tumor and fallopian tubes were collected. Immunohistochemistry methods were used to analyze the expression of P53, PAX8, and Calretinin. The relationship between these protein levels and the classification of ovarian tumors was evaluated.
Results: In epithelial ovarian cancer, the P53 or PAX8 was correlated with the occurrence of high-grade carcinoma, while the calretinin was correlated with the occurrence of low-grade carcinoma (P<0.05). The combination of PAX8 with Calretinin was correlated with the grade of ovarian tumor (P<0.05). The combination of P53 with Calretinin was correlated with the grade of tumor (P<0.05). The combination of P53 with PAX8 was correlated with the grade of tumor (P<0.05). The expression of P53 in fallopian tubes was correlated with the malignant degree of epithelial ovarian cancer (P<</abstract><cop>China</cop><pmid>31303616</pmid><doi>10.11817/j.issn.1672-7347.2019.05.009</doi><tpages>7</tpages></addata></record> |
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| ispartof | Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban, 2019-05, Vol.44 (5), p.528-534 |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Carcinoma, Ovarian Epithelial Epithelium Fallopian Tubes Female Humans Ovarian Neoplasms PAX8 Transcription Factor |
| title | Molecular markers derived from ovarian cancer and its correlation with the types of oviductal epithelial lesions |
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