The vulvar immunohistochemical panel (VIP) project: molecular profiles of vulvar Paget’s disease

Purpose To investigate the expression of biological markers in primary vulvar Paget’s disease (VPD). Methods Forty-one patients referred to a single major Center for Gynecologic Oncology from January 2008 to June 2018 were enrolled retrospectively: 30 non-invasive-VPD and 11 invasive-VPD. A total nu...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2019-09, Vol.145 (9), p.2211-2225
Hauptverfasser:	Garganese, Giorgia, Inzani, Frediano, Mantovani, Giulia, Santoro, Angela, Valente, Michele, Babini, Gabriele, Petruzzellis, Giuliana, Fragomeni, Simona Maria, Gentileschi, Stefano, Bove, Sonia, Franchi, Massimo, Angelico, Giuseppe, Fagotti, Anna, Scambia, Giovanni, Zannoni, Gian Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers Cancer Research CD3 antigen Clinical trials Cluster analysis Epidermal growth factor receptors ErbB-2 protein Female Genital cancers Gynecological cancer Hematology Humans Immunohistochemistry - methods Internal Medicine Learning algorithms Lymph nodes Lymphatic Metastasis Medicine Medicine & Public Health Metabolome Metastases Middle Aged MLH1 protein MSH2 protein MSH6 protein Neoplasm Proteins - analysis Neoplasm Proteins - metabolism Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - pathology Oncology Original Article – Cancer Research p53 Protein Paget Disease, Extramammary - diagnosis Paget Disease, Extramammary - metabolism Paget Disease, Extramammary - pathology PD-L1 protein Proteomics - methods Retrospective Studies Vascular endothelial growth factor Vulvar Neoplasms - diagnosis Vulvar Neoplasms - metabolism Vulvar Neoplasms - pathology
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