cDNA cloning, prokaryotic expression and functional analysis of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) in Pogostemon cablin

Pogostemon cablin is an important commercial source of patchouli oil, whose main active ingredient is patchouli alcohol. This sesquiterpene is a product of the mevalonate pathway, in which 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) is the rate-limiting enzyme. In this study, P. cablin...

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Veröffentlicht in:	Protein expression and purification 2019-11, Vol.163, p.105454-105454, Article 105454
Hauptverfasser:	Zhang, Guixiang, Wu, Yougen, Haq Muhammad, Zeeshan Ul, Yang, Yuzhang, Yu, Jing, Zhang, Junfeng, Yang, Dongmei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cloning, Molecular DNA, Complementary Escherichia coli HMGCR Hydroxymethylglutaryl CoA Reductases - genetics Hydroxymethylglutaryl CoA Reductases - metabolism Mevalonic Acid - analogs & derivatives Mevalonic Acid - metabolism Patchouli alcohol Pogostemon - enzymology Pogostemon - genetics Pogostemon cablin Prokaryotic expression Sesquiterpenes - metabolism
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