Characterization of Gut Microbiota, Bile Acid Metabolism, and Cytokines in Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC), a type of bile duct cancer, has a high mortality rate. Gut microbiota, bile acid (BA) metabolism, and cytokines have not been characterized in patients with ICC, and better noninvasive diagnostic approaches for ICC are essential to be established. Therefore, in...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2020-03, Vol.71 (3), p.893-906
Hauptverfasser:	Jia, Xiaodong, Lu, Shanshan, Zeng, Zhen, Liu, Qingyan, Dong, Zheng, Chen, Yan, Zhu, Zhenyu, Hong, Zhixian, Zhang, Ting, Du, Guifang, Xiang, Jiao, Wu, Dawei, Bai, Wenlin, Yang, Bin, Li, Yinyin, Huang, Jiagan, Li, Haiyang, Safadi, Rifaat, Lu, Yinying
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Acids Actinobacteria - isolation & purification Animal models Animals Bile Bile Acids and Salts - metabolism Bile Duct Neoplasms - immunology Bile Duct Neoplasms - metabolism Bile Duct Neoplasms - microbiology Bile Duct Neoplasms - pathology Bile ducts Chenodeoxycholic acid Cholangiocarcinoma Cholangiocarcinoma - immunology Cholangiocarcinoma - metabolism Cholangiocarcinoma - microbiology Cholangiocarcinoma - pathology Cirrhosis Cytokines Cytokines - blood Gastrointestinal Microbiome - physiology Hepatocellular carcinoma Hepatology Humans Inflammation Intestinal microflora Lactobacillus Lactobacillus - isolation & purification Liver cancer Liver cirrhosis Male Medical prognosis Metabolism Mice Mice, Inbred BALB C Microbiota Neoplasm Invasiveness Plasma Taurocholic acid Tauroursodeoxycholic acid
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