Correlation between DCE-MRI quantitative perfusion histogram parameters, apparent diffusion coefficient and Ki-67 in different pathological types of lung cancer
To explore the efficacy of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) histogram molecular imaging index, apparent diffusion coefficient (ADC) in different types of lung cancer and explore their correlation with Ki-67. A total of 33 cases of lung cancer patients confirmed by patho...
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| Veröffentlicht in: | Zhong hua yi xue za zhi 2019-06, Vol.99 (21), p.1645-1650 |
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| container_title | Zhong hua yi xue za zhi |
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| creator | Huang, Y N Zhao, Z H Mao, H J Yang, J F Wang, T Zhao, L Yang, L M Yu, G M Wang, C |
| description | To explore the efficacy of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) histogram molecular imaging index, apparent diffusion coefficient (ADC) in different types of lung cancer and explore their correlation with Ki-67.
A total of 33 cases of lung cancer patients confirmed by pathology in Shaoxing People's Hospital from March 2017 to March 2018 were collected, 28 males and 5 females aged 50-85 years old, including 15 cases of squamous cell carcinoma, 12 cases of adenocarcinoma, and 6 cases of small cell carcinoma. All patients performed DCE-MRI and DWI imaging within one week before surgery or puncture. ADC values, DCE-MRI quantitative perfusion parameters by histogram metrics analysis (mean value, skewness, kurtosis, uniformity, entropy, energy, quantile) of K(trans), K(ep), V(e), and V(p) were then collected. Ki-67 expression in lung cancer tissue was detected by immunohistochemical method. One-way analysis of variance and least significant difference were used to compare the differences a |
| doi_str_mv | 10.3760/cma.j.issn.0376-2491.2019.21.011 |
| format | Article |
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| issn | 0376-2491 |
| language | chi |
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| source | MEDLINE; EZB Electronic Journals Library |
| subjects | Aged Aged, 80 and over Diffusion Magnetic Resonance Imaging Female Humans Ki-67 Antigen Lung Neoplasms Magnetic Resonance Imaging Male Middle Aged Perfusion |
| title | Correlation between DCE-MRI quantitative perfusion histogram parameters, apparent diffusion coefficient and Ki-67 in different pathological types of lung cancer |
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