Correlation between the expression of STOX1 in placenta of patients with early onset preeclampsia
To investigate the relationship of STOX1expression and pathogenesis of early onset preeclampsia. 65 cases of preeclampsia women who delivered in Shanghai Pudong Hospital from October 2015 to June 2018, were recruited, which included 31 cases with early onset preeclampsia (early onset group, gestatio...
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Veröffentlicht in: | Zhong hua yi xue za zhi 2019-06, Vol.99 (21), p.1664-1668 |
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creator | Zhao, Y M Duan, Y C Zhu, J L Ding, H Y Shan, Y Zhu, Z P |
description | To investigate the relationship of STOX1expression and pathogenesis of early onset preeclampsia.
65 cases of preeclampsia women who delivered in Shanghai Pudong Hospital from October 2015 to June 2018, were recruited, which included 31 cases with early onset preeclampsia (early onset group, gestational week |
doi_str_mv | 10.3760/cma.j.issn.0376-2491.2019.21.015 |
format | Article |
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65 cases of preeclampsia women who delivered in Shanghai Pudong Hospital from October 2015 to June 2018, were recruited, which included 31 cases with early onset preeclampsia (early onset group, gestational week<34 weeks) and 34 patients with late onset preeclampsia (late onset group, gestational week ≥34 weeks). 34 cases women who received caesarean section because of pelvic structural deformities, breech presentation, macrosomia and social factors were included as the control group(gestational week ≥34 weeks) were selected as control group.The expression and localization of STOX1 mRNA and protein in placenta of three groups of maternal were evaluated by immunohistochemistry SP, RT-qPCR and Western blotting.
(1) The expression of STOX1 in placenta mainly distributed in the cytoplasm of placental syncytiotrophoblasts, cytotrophoblasts, vascular endothelial and mesenchymal cells, a few in the cell nucleus.The stain</description><identifier>ISSN: 0376-2491</identifier><identifier>DOI: 10.3760/cma.j.issn.0376-2491.2019.21.015</identifier><identifier>PMID: 31189268</identifier><language>chi</language><publisher>China</publisher><subject>Carrier Proteins - genetics ; Case-Control Studies ; Cesarean Section ; China ; Female ; Humans ; Placenta ; Pre-Eclampsia - genetics ; Pregnancy ; Trophoblasts</subject><ispartof>Zhong hua yi xue za zhi, 2019-06, Vol.99 (21), p.1664-1668</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31189268$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhao, Y M</creatorcontrib><creatorcontrib>Duan, Y C</creatorcontrib><creatorcontrib>Zhu, J L</creatorcontrib><creatorcontrib>Ding, H Y</creatorcontrib><creatorcontrib>Shan, Y</creatorcontrib><creatorcontrib>Zhu, Z P</creatorcontrib><title>Correlation between the expression of STOX1 in placenta of patients with early onset preeclampsia</title><title>Zhong hua yi xue za zhi</title><addtitle>Zhonghua Yi Xue Za Zhi</addtitle><description>To investigate the relationship of STOX1expression and pathogenesis of early onset preeclampsia.
65 cases of preeclampsia women who delivered in Shanghai Pudong Hospital from October 2015 to June 2018, were recruited, which included 31 cases with early onset preeclampsia (early onset group, gestational week<34 weeks) and 34 patients with late onset preeclampsia (late onset group, gestational week ≥34 weeks). 34 cases women who received caesarean section because of pelvic structural deformities, breech presentation, macrosomia and social factors were included as the control group(gestational week ≥34 weeks) were selected as control group.The expression and localization of STOX1 mRNA and protein in placenta of three groups of maternal were evaluated by immunohistochemistry SP, RT-qPCR and Western blotting.
(1) The expression of STOX1 in placenta mainly distributed in the cytoplasm of placental syncytiotrophoblasts, cytotrophoblasts, vascular endothelial and mesenchymal cells, a few in the cell nucleus.The stain</description><subject>Carrier Proteins - genetics</subject><subject>Case-Control Studies</subject><subject>Cesarean Section</subject><subject>China</subject><subject>Female</subject><subject>Humans</subject><subject>Placenta</subject><subject>Pre-Eclampsia - genetics</subject><subject>Pregnancy</subject><subject>Trophoblasts</subject><issn>0376-2491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kLtOAzEQRV2ASBTyC8hlmjUee58linhJkVKQgm4164wVo32xdhTy9xgRaGZGR_dMcRlbgRS6yOW96VB8COd9L2QEiUorEEpCJRQICdkVm__zGVt67xqZFrpSUsENm2mAslJ5OWe4HqaJWgxu6HlD4UTU83AgTl_jRNGLeLD8bbd9B-56PrZoqA_4A8doxdvzkwsHTji1Zz70ngKPKpkWu9E7vGXXFltPy8tesN3T4279kmy2z6_rh00ygspDUlZFBSUSmizfk7JxSJ2RsUrrNM9KS0qRTQvCEhCNphKtpSYlyPIMjF6w1e_bcRo-j-RD3TlvqG2xp-Hoa6WyopAyTyFG7y7RY9PRvh4n1-F0rv9a0d-TtWmU</recordid><startdate>20190604</startdate><enddate>20190604</enddate><creator>Zhao, Y M</creator><creator>Duan, Y C</creator><creator>Zhu, J L</creator><creator>Ding, H Y</creator><creator>Shan, Y</creator><creator>Zhu, Z P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20190604</creationdate><title>Correlation between the expression of STOX1 in placenta of patients with early onset preeclampsia</title><author>Zhao, Y M ; Duan, Y C ; Zhu, J L ; Ding, H Y ; Shan, Y ; Zhu, Z P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-897918aeac56de2f6de035ecf2334658fe22ef47ea81aac3e8affeb4e15651c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2019</creationdate><topic>Carrier Proteins - genetics</topic><topic>Case-Control Studies</topic><topic>Cesarean Section</topic><topic>China</topic><topic>Female</topic><topic>Humans</topic><topic>Placenta</topic><topic>Pre-Eclampsia - genetics</topic><topic>Pregnancy</topic><topic>Trophoblasts</topic><toplevel>online_resources</toplevel><creatorcontrib>Zhao, Y M</creatorcontrib><creatorcontrib>Duan, Y C</creatorcontrib><creatorcontrib>Zhu, J L</creatorcontrib><creatorcontrib>Ding, H Y</creatorcontrib><creatorcontrib>Shan, Y</creatorcontrib><creatorcontrib>Zhu, Z P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhong hua yi xue za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhao, Y M</au><au>Duan, Y C</au><au>Zhu, J L</au><au>Ding, H Y</au><au>Shan, Y</au><au>Zhu, Z P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Correlation between the expression of STOX1 in placenta of patients with early onset preeclampsia</atitle><jtitle>Zhong hua yi xue za zhi</jtitle><addtitle>Zhonghua Yi Xue Za Zhi</addtitle><date>2019-06-04</date><risdate>2019</risdate><volume>99</volume><issue>21</issue><spage>1664</spage><epage>1668</epage><pages>1664-1668</pages><issn>0376-2491</issn><abstract>To investigate the relationship of STOX1expression and pathogenesis of early onset preeclampsia.
65 cases of preeclampsia women who delivered in Shanghai Pudong Hospital from October 2015 to June 2018, were recruited, which included 31 cases with early onset preeclampsia (early onset group, gestational week<34 weeks) and 34 patients with late onset preeclampsia (late onset group, gestational week ≥34 weeks). 34 cases women who received caesarean section because of pelvic structural deformities, breech presentation, macrosomia and social factors were included as the control group(gestational week ≥34 weeks) were selected as control group.The expression and localization of STOX1 mRNA and protein in placenta of three groups of maternal were evaluated by immunohistochemistry SP, RT-qPCR and Western blotting.
(1) The expression of STOX1 in placenta mainly distributed in the cytoplasm of placental syncytiotrophoblasts, cytotrophoblasts, vascular endothelial and mesenchymal cells, a few in the cell nucleus.The stain</abstract><cop>China</cop><pmid>31189268</pmid><doi>10.3760/cma.j.issn.0376-2491.2019.21.015</doi><tpages>5</tpages></addata></record> |
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subjects | Carrier Proteins - genetics Case-Control Studies Cesarean Section China Female Humans Placenta Pre-Eclampsia - genetics Pregnancy Trophoblasts |
title | Correlation between the expression of STOX1 in placenta of patients with early onset preeclampsia |
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