Polymorphisms in the BDNF and BDNFOS genes are associated with hypothalamus-pituitary axis regulation in major depression

Major depression is a stress-related disorder with robust clinical and preclinical data implicating that both, dysregulation of the hypothalamus-pituitary-adrenocortical (HPA) axis and of the neurotrophin system of the brain are involved in the pathophysiology. Genetic variations within the brain-de...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2019-12, Vol.95, p.109686-109686, Article 109686
Hauptverfasser:	Hennings, Johannes M., Kohli, Martin A., Uhr, Manfred, Holsboer, Florian, Ising, Marcus, Lucae, Susanne
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidepressant BDNF Depression HPA-axis Neurotrophin Pharmacogenetics
Online-Zugang:	Volltext
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