Zn(OTf) 2 -mediated annulations of N -propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds

Intramolecular hydroarylations of -propargylated tetrahydrocarbolines were efficiently mediated using a unique combination of Zn(OTf) with -BuOH under neutral conditions. Use of the artificial force induced reaction method in the global reaction route mapping strategy provided insights into the Zn(O...

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Veröffentlicht in:	Chemical science (Cambridge) 2019-06, Vol.10 (22), p.5686-5698
Hauptverfasser:	Yorimoto, Sadaiwa, Tsubouchi, Akira, Mizoguchi, Haruki, Oikawa, Hideaki, Tsunekawa, Yoshiaki, Ichino, Tomoya, Maeda, Satoshi, Oguri, Hiroki
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbonyl groups Carbonyls Chemical reactions Crystallography Mapping Organic chemistry Scaffolds Solvents Substrates
Online-Zugang:	Volltext
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