The Low Dose Colchicine after Myocardial Infarction (LoDoCo-MI) study: A pilot randomized placebo controlled trial of colchicine following acute myocardial infarction

Following an acute myocardial infarction (MI), patients with persistently elevated biomarkers of inflammation, in particular C-reactive protein (CRP), are at significantly increased risk of further cardiovascular events. Colchicine is a unique anti-inflammatory medication that has shown promise in r...

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Veröffentlicht in:	The American heart journal 2019-09, Vol.215, p.62-69
Hauptverfasser:	Hennessy, Thomas, Soh, Linda, Bowman, Mitchell, Kurup, Rahul, Schultz, Carl, Patel, Sanjay, Hillis, Graham S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biomarkers - blood C-reactive protein C-Reactive Protein - metabolism Cardiovascular disease Cardiovascular diseases Clinical trials Colchicine Colchicine - administration & dosage Coronary artery disease Cytokines Dose-Response Relationship, Drug Double-Blind Method Female Follow-Up Studies Glycoproteins Health risk assessment Health risks Heart attacks Heart diseases Hemoglobin Humans Inflammation Inflammation - blood Inflammation - drug therapy Inflammation - etiology Laboratories Levels Male Middle Aged Myocardial infarction Myocardial Infarction - blood Myocardial Infarction - complications Neutrophils Pilot Projects Proteins Randomization Reduction Retrospective Studies Time Factors Treatment Outcome
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