Role of TLR4/NADPH oxidase 4 pathway in promoting cell death through autophagy and ferroptosis during heart failure

Loss of myocytes caused by cell death plays a key role during heart failure (HF). Activated autophagy and increased ferroptosis have been observed in HF and proved to promote its progression. However, the underlying mechanisms remain unclear. Here, results from integrated bioinformatical analysis sh...

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Veröffentlicht in:	Biochemical and biophysical research communications 2019-08, Vol.516 (1), p.37-43
Hauptverfasser:	Chen, Xiaoqing, Xu, Sudan, Zhao, Chunxia, Liu, Bei
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Ferroptosis Heart failure NOX4 TLR4
Online-Zugang:	Volltext
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