Cross-sectional associations between [18F]GTP1 tau PET and cognition in Alzheimer's disease

The regional relationships between tau positron emission tomography (PET) imaging and cognitive impairment in Alzheimer's disease (AD) remain uncertain. We examined cross-sectional associations between cognitive performance, cerebral uptake of the novel tau PET tracer [18F]GTP1, and other neuro...

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Veröffentlicht in:	Neurobiology of aging 2019-09, Vol.81, p.138-145
Hauptverfasser:	Teng, Edmond, Ward, Michael, Manser, Paul T., Sanabria-Bohorquez, Sandra, Ray, Rebecca D., Wildsmith, Kristin R., Baker, Suzanne, Kerchner, Geoffrey A., Weimer, Robby M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - diagnostic imaging Alzheimer Disease - psychology Alzheimer's disease Brain - diagnostic imaging Brain - metabolism Clinical trial Cognition Cognitive Dysfunction - diagnostic imaging Cognitive Dysfunction - psychology Cross-Sectional Studies Female Fluorine Radioisotopes - metabolism Humans Male Middle Aged Neuroimaging PET Positron-Emission Tomography Radiopharmaceuticals - metabolism Severity of Illness Index Tau tau Proteins - metabolism
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