Epidemiology and risk factors for carbapenem-resistant Enterobacteriaceae colonisation and infections: case-controlled study from an academic medical center in a southern area of China
ABSTRACT OBJECTIVE While the emergence and spread of carbapenem-resistant Enterobacteriaceae (CRE) and related infections pose serious threats to global public health, the epidemiology and associated risk factors remain poorly understood and vary by geography. METHODS In a case-controlled retrospect...
Gespeichert in:
| Veröffentlicht in: | Pathogens and Disease 2019-06, Vol.77 (4), p.1 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 4 |
| container_start_page | 1 |
| container_title | Pathogens and Disease |
| container_volume | 77 |
| creator | Fang, Lili Lu, Xiaohui Xu, Heping Ma, Xiaobo Chen, Yilan Liu, Yue Hong, Guolin Liang, Xianming |
| description | ABSTRACT
OBJECTIVE
While the emergence and spread of carbapenem-resistant Enterobacteriaceae (CRE) and related infections pose serious threats to global public health, the epidemiology and associated risk factors remain poorly understood and vary by geography.
METHODS
In a case-controlled retrospective study, we examined the prevalence, patient background and risk factors for CRE colonisation and infections, and all patient-derived CRE from January 2015 to January 2017. Isolated carbapenem-susceptible Enterobacteriaceae (CSE) from 2875 enrolled patients were randomly selected during the study.
RESULTS
CRE colonisation and infections detection rates were 47/2875 (1.6%). Respiratory tract specimens were most frequently seen in 20/47 (42.6%) cases. Klebsiella pneumoniae was the main isolate in 35/47 (74.5%) CRE. As for carbapenemase, KPC-2-producing bacteria was most frequently detected in 38/47 (80.9%) Enterobacteriaceae. No underlying conditions (P = 0.004), pulmonary diseases (P = 0.018) and no antibiotics used prior to culture within 30 days (P |
| doi_str_mv | 10.1093/femspd/ftz034 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2253828049</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A606881656</galeid><oup_id>10.1093/femspd/ftz034</oup_id><sourcerecordid>A606881656</sourcerecordid><originalsourceid>FETCH-LOGICAL-c421t-a2cdcb8c6a627c8a321b33afa38affd1916a4ceb6a38d45863df2b2c1e2ca7a53</originalsourceid><addsrcrecordid>eNqFkk1v1DAQhiMEolXpkSuyxIVL2thOvA63arV8SJW4gMQtmkzGrUtiB9s5LL-Mn4dDlg9xwRePR8-8mnk9RfGcV1e8auW1oSnOw7VJ3ypZPyrORVW3pZLi8-O_4rPiMsaHKh_dcL1TT4szyYXmreTnxffDbAearB_93ZGBG1iw8QszgMmHyIwPDCH0MJOjqQwUbUzgEju4RMH3GaNgAQmIYdZwNkKy3v1Uss4Qrq_4OotEKtG7FPw40sBiWoYjM8FPGWWAsDaBbKLBIowMadXPCgxY9Eu6p5DDQMC8Yft76-BZ8cTAGOnydF8Un94cPu7flbcf3r7f39yWWAueShA4YK9RgRI71CAF76UEA1KDMQNvuYIaqVc5MdSNVnIwohfISSDsoJEXxatNdw7-60IxdZONSOMIjvwSOyEaqYXOZmf05T_og1-Cy911QlY72fJGrdTVRt3BSF32yKeQ5z854B0Zm_M3qlJac9WoXFBuBRh8jIFMNwc7QTh2vOrWNei2Nei2Ncj8i1MbS5_9_E3_-vQ_I_ll_o_WD9OzwqE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2307391569</pqid></control><display><type>article</type><title>Epidemiology and risk factors for carbapenem-resistant Enterobacteriaceae colonisation and infections: case-controlled study from an academic medical center in a southern area of China</title><source>MEDLINE</source><source>Oxford Journals Open Access Collection</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Fang, Lili ; Lu, Xiaohui ; Xu, Heping ; Ma, Xiaobo ; Chen, Yilan ; Liu, Yue ; Hong, Guolin ; Liang, Xianming</creator><creatorcontrib>Fang, Lili ; Lu, Xiaohui ; Xu, Heping ; Ma, Xiaobo ; Chen, Yilan ; Liu, Yue ; Hong, Guolin ; Liang, Xianming</creatorcontrib><description>ABSTRACT
OBJECTIVE
While the emergence and spread of carbapenem-resistant Enterobacteriaceae (CRE) and related infections pose serious threats to global public health, the epidemiology and associated risk factors remain poorly understood and vary by geography.
METHODS
In a case-controlled retrospective study, we examined the prevalence, patient background and risk factors for CRE colonisation and infections, and all patient-derived CRE from January 2015 to January 2017. Isolated carbapenem-susceptible Enterobacteriaceae (CSE) from 2875 enrolled patients were randomly selected during the study.
RESULTS
CRE colonisation and infections detection rates were 47/2875 (1.6%). Respiratory tract specimens were most frequently seen in 20/47 (42.6%) cases. Klebsiella pneumoniae was the main isolate in 35/47 (74.5%) CRE. As for carbapenemase, KPC-2-producing bacteria was most frequently detected in 38/47 (80.9%) Enterobacteriaceae. No underlying conditions (P = 0.004), pulmonary diseases (P = 0.018) and no antibiotics used prior to culture within 30 days (P < 0.001) were statistically significant between the CRE and CSE groups.
CONCLUSION
Klebsiellapneumoniae was the main isolate of CRE. The blaKPC-2 was the predominant CRE gene. Underlying conditions especially pulmonary diseases and antibiotics used prior to culture within 30 days represented key risk factors for acquisition of CRE.</description><identifier>ISSN: 2049-632X</identifier><identifier>EISSN: 2049-632X</identifier><identifier>DOI: 10.1093/femspd/ftz034</identifier><identifier>PMID: 31281931</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Academic Medical Centers ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibiotics ; Carbapenem-Resistant Enterobacteriaceae - isolation & purification ; Carbapenemase ; Care and treatment ; Carrier State - epidemiology ; Carrier State - microbiology ; Case-Control Studies ; Child ; Child, Preschool ; China ; Colonization ; Control methods ; CRE bacteria ; Culture ; Development and progression ; Enterobacteriaceae ; Enterobacteriaceae - classification ; Enterobacteriaceae - isolation & purification ; Enterobacteriaceae infections ; Enterobacteriaceae Infections - epidemiology ; Epidemiology ; Female ; Geography ; Health care facilities ; Humans ; Infant ; Infant, Newborn ; Infections ; Klebsiella ; Lung diseases ; Male ; Medical geography ; Medical research ; Medicine, Experimental ; Methods ; Middle Aged ; Prevalence ; Public health ; Public health administration ; Resistance factors ; Respiratory tract ; Retrospective Studies ; Risk analysis ; Risk Factors ; Statistical analysis ; Young Adult</subject><ispartof>Pathogens and Disease, 2019-06, Vol.77 (4), p.1</ispartof><rights>The Author(s) 2019. Published by Oxford University Press on behalf of FEMS. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2019</rights><rights>FEMS 2019.</rights><rights>COPYRIGHT 2019 Oxford University Press</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-a2cdcb8c6a627c8a321b33afa38affd1916a4ceb6a38d45863df2b2c1e2ca7a53</citedby><cites>FETCH-LOGICAL-c421t-a2cdcb8c6a627c8a321b33afa38affd1916a4ceb6a38d45863df2b2c1e2ca7a53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31281931$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fang, Lili</creatorcontrib><creatorcontrib>Lu, Xiaohui</creatorcontrib><creatorcontrib>Xu, Heping</creatorcontrib><creatorcontrib>Ma, Xiaobo</creatorcontrib><creatorcontrib>Chen, Yilan</creatorcontrib><creatorcontrib>Liu, Yue</creatorcontrib><creatorcontrib>Hong, Guolin</creatorcontrib><creatorcontrib>Liang, Xianming</creatorcontrib><title>Epidemiology and risk factors for carbapenem-resistant Enterobacteriaceae colonisation and infections: case-controlled study from an academic medical center in a southern area of China</title><title>Pathogens and Disease</title><addtitle>Pathog Dis</addtitle><description>ABSTRACT
OBJECTIVE
While the emergence and spread of carbapenem-resistant Enterobacteriaceae (CRE) and related infections pose serious threats to global public health, the epidemiology and associated risk factors remain poorly understood and vary by geography.
METHODS
In a case-controlled retrospective study, we examined the prevalence, patient background and risk factors for CRE colonisation and infections, and all patient-derived CRE from January 2015 to January 2017. Isolated carbapenem-susceptible Enterobacteriaceae (CSE) from 2875 enrolled patients were randomly selected during the study.
RESULTS
CRE colonisation and infections detection rates were 47/2875 (1.6%). Respiratory tract specimens were most frequently seen in 20/47 (42.6%) cases. Klebsiella pneumoniae was the main isolate in 35/47 (74.5%) CRE. As for carbapenemase, KPC-2-producing bacteria was most frequently detected in 38/47 (80.9%) Enterobacteriaceae. No underlying conditions (P = 0.004), pulmonary diseases (P = 0.018) and no antibiotics used prior to culture within 30 days (P < 0.001) were statistically significant between the CRE and CSE groups.
CONCLUSION
Klebsiellapneumoniae was the main isolate of CRE. The blaKPC-2 was the predominant CRE gene. Underlying conditions especially pulmonary diseases and antibiotics used prior to culture within 30 days represented key risk factors for acquisition of CRE.</description><subject>Academic Medical Centers</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antibiotics</subject><subject>Carbapenem-Resistant Enterobacteriaceae - isolation & purification</subject><subject>Carbapenemase</subject><subject>Care and treatment</subject><subject>Carrier State - epidemiology</subject><subject>Carrier State - microbiology</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>China</subject><subject>Colonization</subject><subject>Control methods</subject><subject>CRE bacteria</subject><subject>Culture</subject><subject>Development and progression</subject><subject>Enterobacteriaceae</subject><subject>Enterobacteriaceae - classification</subject><subject>Enterobacteriaceae - isolation & purification</subject><subject>Enterobacteriaceae infections</subject><subject>Enterobacteriaceae Infections - epidemiology</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Geography</subject><subject>Health care facilities</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infections</subject><subject>Klebsiella</subject><subject>Lung diseases</subject><subject>Male</subject><subject>Medical geography</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Prevalence</subject><subject>Public health</subject><subject>Public health administration</subject><subject>Resistance factors</subject><subject>Respiratory tract</subject><subject>Retrospective Studies</subject><subject>Risk analysis</subject><subject>Risk Factors</subject><subject>Statistical analysis</subject><subject>Young Adult</subject><issn>2049-632X</issn><issn>2049-632X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkk1v1DAQhiMEolXpkSuyxIVL2thOvA63arV8SJW4gMQtmkzGrUtiB9s5LL-Mn4dDlg9xwRePR8-8mnk9RfGcV1e8auW1oSnOw7VJ3ypZPyrORVW3pZLi8-O_4rPiMsaHKh_dcL1TT4szyYXmreTnxffDbAearB_93ZGBG1iw8QszgMmHyIwPDCH0MJOjqQwUbUzgEju4RMH3GaNgAQmIYdZwNkKy3v1Uss4Qrq_4OotEKtG7FPw40sBiWoYjM8FPGWWAsDaBbKLBIowMadXPCgxY9Eu6p5DDQMC8Yft76-BZ8cTAGOnydF8Un94cPu7flbcf3r7f39yWWAueShA4YK9RgRI71CAF76UEA1KDMQNvuYIaqVc5MdSNVnIwohfISSDsoJEXxatNdw7-60IxdZONSOMIjvwSOyEaqYXOZmf05T_og1-Cy911QlY72fJGrdTVRt3BSF32yKeQ5z854B0Zm_M3qlJac9WoXFBuBRh8jIFMNwc7QTh2vOrWNei2Nei2Ncj8i1MbS5_9_E3_-vQ_I_ll_o_WD9OzwqE</recordid><startdate>20190601</startdate><enddate>20190601</enddate><creator>Fang, Lili</creator><creator>Lu, Xiaohui</creator><creator>Xu, Heping</creator><creator>Ma, Xiaobo</creator><creator>Chen, Yilan</creator><creator>Liu, Yue</creator><creator>Hong, Guolin</creator><creator>Liang, Xianming</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IAO</scope><scope>3V.</scope><scope>7T7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20190601</creationdate><title>Epidemiology and risk factors for carbapenem-resistant Enterobacteriaceae colonisation and infections: case-controlled study from an academic medical center in a southern area of China</title><author>Fang, Lili ; Lu, Xiaohui ; Xu, Heping ; Ma, Xiaobo ; Chen, Yilan ; Liu, Yue ; Hong, Guolin ; Liang, Xianming</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-a2cdcb8c6a627c8a321b33afa38affd1916a4ceb6a38d45863df2b2c1e2ca7a53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Academic Medical Centers</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antibiotics</topic><topic>Carbapenem-Resistant Enterobacteriaceae - isolation & purification</topic><topic>Carbapenemase</topic><topic>Care and treatment</topic><topic>Carrier State - epidemiology</topic><topic>Carrier State - microbiology</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>China</topic><topic>Colonization</topic><topic>Control methods</topic><topic>CRE bacteria</topic><topic>Culture</topic><topic>Development and progression</topic><topic>Enterobacteriaceae</topic><topic>Enterobacteriaceae - classification</topic><topic>Enterobacteriaceae - isolation & purification</topic><topic>Enterobacteriaceae infections</topic><topic>Enterobacteriaceae Infections - epidemiology</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Geography</topic><topic>Health care facilities</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infections</topic><topic>Klebsiella</topic><topic>Lung diseases</topic><topic>Male</topic><topic>Medical geography</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Methods</topic><topic>Middle Aged</topic><topic>Prevalence</topic><topic>Public health</topic><topic>Public health administration</topic><topic>Resistance factors</topic><topic>Respiratory tract</topic><topic>Retrospective Studies</topic><topic>Risk analysis</topic><topic>Risk Factors</topic><topic>Statistical analysis</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fang, Lili</creatorcontrib><creatorcontrib>Lu, Xiaohui</creatorcontrib><creatorcontrib>Xu, Heping</creatorcontrib><creatorcontrib>Ma, Xiaobo</creatorcontrib><creatorcontrib>Chen, Yilan</creatorcontrib><creatorcontrib>Liu, Yue</creatorcontrib><creatorcontrib>Hong, Guolin</creatorcontrib><creatorcontrib>Liang, Xianming</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale Academic OneFile</collection><collection>ProQuest Central (Corporate)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Pathogens and Disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fang, Lili</au><au>Lu, Xiaohui</au><au>Xu, Heping</au><au>Ma, Xiaobo</au><au>Chen, Yilan</au><au>Liu, Yue</au><au>Hong, Guolin</au><au>Liang, Xianming</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epidemiology and risk factors for carbapenem-resistant Enterobacteriaceae colonisation and infections: case-controlled study from an academic medical center in a southern area of China</atitle><jtitle>Pathogens and Disease</jtitle><addtitle>Pathog Dis</addtitle><date>2019-06-01</date><risdate>2019</risdate><volume>77</volume><issue>4</issue><spage>1</spage><pages>1-</pages><issn>2049-632X</issn><eissn>2049-632X</eissn><abstract>ABSTRACT
OBJECTIVE
While the emergence and spread of carbapenem-resistant Enterobacteriaceae (CRE) and related infections pose serious threats to global public health, the epidemiology and associated risk factors remain poorly understood and vary by geography.
METHODS
In a case-controlled retrospective study, we examined the prevalence, patient background and risk factors for CRE colonisation and infections, and all patient-derived CRE from January 2015 to January 2017. Isolated carbapenem-susceptible Enterobacteriaceae (CSE) from 2875 enrolled patients were randomly selected during the study.
RESULTS
CRE colonisation and infections detection rates were 47/2875 (1.6%). Respiratory tract specimens were most frequently seen in 20/47 (42.6%) cases. Klebsiella pneumoniae was the main isolate in 35/47 (74.5%) CRE. As for carbapenemase, KPC-2-producing bacteria was most frequently detected in 38/47 (80.9%) Enterobacteriaceae. No underlying conditions (P = 0.004), pulmonary diseases (P = 0.018) and no antibiotics used prior to culture within 30 days (P < 0.001) were statistically significant between the CRE and CSE groups.
CONCLUSION
Klebsiellapneumoniae was the main isolate of CRE. The blaKPC-2 was the predominant CRE gene. Underlying conditions especially pulmonary diseases and antibiotics used prior to culture within 30 days represented key risk factors for acquisition of CRE.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>31281931</pmid><doi>10.1093/femspd/ftz034</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2049-632X |
| ispartof | Pathogens and Disease, 2019-06, Vol.77 (4), p.1 |
| issn | 2049-632X 2049-632X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2253828049 |
| source | MEDLINE; Oxford Journals Open Access Collection; PubMed Central; Alma/SFX Local Collection |
| subjects | Academic Medical Centers Adolescent Adult Aged Aged, 80 and over Antibiotics Carbapenem-Resistant Enterobacteriaceae - isolation & purification Carbapenemase Care and treatment Carrier State - epidemiology Carrier State - microbiology Case-Control Studies Child Child, Preschool China Colonization Control methods CRE bacteria Culture Development and progression Enterobacteriaceae Enterobacteriaceae - classification Enterobacteriaceae - isolation & purification Enterobacteriaceae infections Enterobacteriaceae Infections - epidemiology Epidemiology Female Geography Health care facilities Humans Infant Infant, Newborn Infections Klebsiella Lung diseases Male Medical geography Medical research Medicine, Experimental Methods Middle Aged Prevalence Public health Public health administration Resistance factors Respiratory tract Retrospective Studies Risk analysis Risk Factors Statistical analysis Young Adult |
| title | Epidemiology and risk factors for carbapenem-resistant Enterobacteriaceae colonisation and infections: case-controlled study from an academic medical center in a southern area of China |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T09%3A56%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Epidemiology%20and%20risk%20factors%20for%20carbapenem-resistant%20Enterobacteriaceae%20colonisation%20and%20infections:%20case-controlled%20study%20from%20an%20academic%20medical%20center%20in%20a%20southern%20area%20of%20China&rft.jtitle=Pathogens%20and%20Disease&rft.au=Fang,%20Lili&rft.date=2019-06-01&rft.volume=77&rft.issue=4&rft.spage=1&rft.pages=1-&rft.issn=2049-632X&rft.eissn=2049-632X&rft_id=info:doi/10.1093/femspd/ftz034&rft_dat=%3Cgale_proqu%3EA606881656%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2307391569&rft_id=info:pmid/31281931&rft_galeid=A606881656&rft_oup_id=10.1093/femspd/ftz034&rfr_iscdi=true |