Fluidic Force Microscopy Captures Amyloid Bonds between Microbial Cells

Fluidic Force Microscopy Captures Amyloid Bonds between Microbial Cells

Fluidic force microscopy (FluidFM) is a recent force-controlled pipette technology that enables manipulation of single cells. FluidFM can be used for quantification of forces between single cells, and a novel mode of cell–cell adhesion was uncovered: amyloid-like interactions that mediate homophilic...

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Veröffentlicht in:Trends in microbiology (Regular ed.) 2019-09, Vol.27 (9), p.728-730
Hauptverfasser: Dehullu, Jérôme, Vorholt, Julia A., Lipke, Peter N., Dufrêne, Yves F.
Format: Artikel
Sprache:eng
Schlagworte:
Adhesion
biofilms
Candida albicans
Cell adhesion
Cell adhesion & migration
fluidic force microscopy
functional amyloids
homophilic adhesion
Microorganisms
Microscopy
nanoscale forces
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Zusammenfassung:Fluidic force microscopy (FluidFM) is a recent force-controlled pipette technology that enables manipulation of single cells. FluidFM can be used for quantification of forces between single cells, and a novel mode of cell–cell adhesion was uncovered: amyloid-like interactions that mediate homophilic adhesion in the fungal pathogen Candida albicans.
ISSN:0966-842X
1878-4380
DOI:10.1016/j.tim.2019.06.001