Evaluation of 8‐week glecaprevir/pibrentasvir treatment in direct‐acting antiviral‐naïve noncirrhotic HCV genotype 1 and 2infected patients in a real‐world setting in Japan

Based on high efficacy and safety demonstrated in clinical trials, treatment with glecaprevir/pibrentasvir (G/P) for 8 weeks is recommended for hepatitis C virus (HCV)–infected patients who are direct‐acting antiviral (DAA) naïve, genotype 1 or 2, and noncirrhotic. The aim of this study was to valid...

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Veröffentlicht in:	Journal of viral hepatitis 2019-11, Vol.26 (11), p.1266-1275
Hauptverfasser:	Ikeda, Hiroki, Watanabe, Tsunamasa, Atsukawa, Masanori, Toyoda, Hidenori, Takaguchi, Koichi, Nakamuta, Makoto, Matsumoto, Nobuyuki, Okuse, Chiaki, Tada, Toshifumi, Tsutsui, Akemi, Yamashita, Naoki, Kondo, Chisa, Hayama, Korenobu, Kato, Keizo, Itokawa, Norio, Arai, Taeang, Shimada, Noritomo, Asano, Toru, Uojima, Haruki, Ogawa, Chikara, Mikami, Shigeru, Ikegami, Tadashi, Fukunishi, Shinya, Asai, Akira, Iio, Etsuko, Tsubota, Akihito, Hiraoka, Atsushi, Nozaki, Akito, Okubo, Hironao, Tachi, Yoshihiko, Moriya, Akio, Oikawa, Tsunekazu, Matsumoto, Yoshihiro, Tsuruoka, Shuichi, Tani, Joji, Kikuchi, Kan, Iwakiri, Katsuhiko, Tanaka, Yasuhito, Kumada, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Amino acids Antiretroviral drugs Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Antiviral drugs Benzimidazoles - therapeutic use Clinical trials Drug Therapy, Combination Female Genotype Genotype & phenotype glecaprevir Hepacivirus - drug effects Hepacivirus - genetics Hepatitis C Hepatitis C - diagnosis Hepatitis C - drug therapy Hepatitis C - virology hepatitis C virus Humans Japan Male Middle Aged Patients pibrentasvir Quinoxalines - therapeutic use real world Sequence Analysis, DNA Sulfonamides - therapeutic use Sustained Virologic Response Treatment Failure Treatment Outcome Young Adult
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