Circulating miR‐99b‐5p as a novel predictor of erosion progression on high‐resolution peripheral quantitative computed tomography in early rheumatoid arthritis: A prospective cohort study

Objectives To compare micro RNA (miRNA) expression: (a) between healthy individuals and early rheumatoid arthritis (ERA) patients with and without erosion on high‐resolution peripheral quantitative computed tomography (HR‐pQCT) at baseline; and (b) to explore whether these miRNAs could inform a sign...

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Veröffentlicht in:	International journal of rheumatic diseases 2019-09, Vol.22 (9), p.1724-1733
Hauptverfasser:	Yue, Jiang, Lau, Terrence C. K., Griffith, James F., Xu, Jiankun, Xiao, Fan, Shi, Lin, Wang, Defeng, Wong, Priscilla C. H., Li, Edmund K., Tam, Lydia P., Li, Martin, Li, Tena K., Mak, Wah Yan, Hung, Vivian, Qin, Ling, Tam, Lai‐Shan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antirheumatic Agents - therapeutic use Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - diagnostic imaging Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - genetics Case-Control Studies Circulating MicroRNA - blood Circulating MicroRNA - genetics Cohort analysis Computed tomography Disease Progression Early Diagnosis early rheumatoid arthritis erosion progression Female Genetic Markers Health risk assessment HR‐pQCT Humans Male Metacarpophalangeal Joint - diagnostic imaging MicroRNAs - blood MicroRNAs - genetics Middle Aged miRNA miRNAs Polymerase chain reaction Predictive Value of Tests Prospective Studies Randomized Controlled Trials as Topic Reproducibility of Results Rheumatoid arthritis Risk Factors Severity of Illness Index Time Factors Tomography, X-Ray Computed Treatment Outcome
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